Proanthocyanidin Block Arrays (PACBAR) for Comprehensive Capture and Delineation of Proanthocyanidin Structures

doi:10.1021/acs.jafc.0c05392

	Proanthocyanidin Block Arrays (PACBAR) for Comprehensive Capture and Delineation of Proanthocyanidin Structures
	Jing, Shuxi 1,2; Zeller, Wayne E.3; Ferreira, Daneel 4,5; Zhou, Bin 6; Nam, Joo-Won 7; Bedran-Russo, Ana 8; Chen, Shao-Nong 1,2; Pauli, Guido F.1,2
刊名	JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
	2020-11-25
卷号	68 期号:47 页码:13541-13549
关键词	proanthocyanidins polyphenols nomenclature structure-activity relationships
ISSN号	0021-8561
DOI	10.1021/acs.jafc.0c05392
通讯作者	Pauli, Guido F.(gfp@uic.edu)
英文摘要	Proanthocyanidins (PACs) are near-ubiquitous and chemically complex metabolites, prototypical of higher plants. Their roles in food/feed/nutrition and ethnomedicine are widely recognized but poorly understood. With the analysis of evidence that underlies this challenge, this perspective identifies shortcomings in capturing and delineating PAC structures as key factors. While several groups have forwarded new representations, a consensus method that captures PAC structures concisely and offers high integrity for electronic storage is required to reduce confusion in this expansive field. The PAC block arrays (PACBAR) system fills this gap by providing precise and human- and machine-readable structural descriptors that capture PAC metabolomic structural diversity. PACBAR enables communication of PAC structures for the development of precise structure-activity relationships and will assist in advancing PAC research to the next level.
资助项目	University of Illinois at Chicago ; Marquette University ; National Institute of Dental and Craniofacial Research (NIDCR)/National Institutes of Health (NIH)[R01 DE021040] ; National Institute of Dental and Craniofacial Research (NIDCR)/National Institutes of Health (NIH)[R56 DE021040] ; National Institute of Dental and Craniofacial Research (NIDCR)/National Institutes of Health (NIH)[R01 DE028194]
WOS研究方向	Agriculture ; Chemistry ; Food Science & Technology
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000595545400022
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/296164]
专题	中国科学院上海药物研究所
通讯作者	Pauli, Guido F.
作者单位	1.Univ Illinois, Coll Pharm, Pharmacognosy Inst, Chicago, IL 60612 USA 2.Univ Illinois, Coll Pharm, Dept Pharmaceut Sci, Chicago, IL 60612 USA 3.ARS, US Dairy Forage Res Ctr, USDA, Madison, WI USA 4.Univ Mississippi, Natl Ctr Nat Prod Res, University, MS 38677 USA 5.Univ Mississippi, Dept Biomol Sci, Div Pharmacognosy, Sch Pharm, University, MS 38677 USA 6.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 7.Yeungnam Univ, Coll Pharm, Gyongsan 38541, Gyeongsangbuk D, South Korea 8.Marquette Univ, Sch Dent, Dept Gen Dent Sci, Milwaukee, WI 53233 USA
推荐引用方式 GB/T 7714	Jing, Shuxi,Zeller, Wayne E.,Ferreira, Daneel,et al. Proanthocyanidin Block Arrays (PACBAR) for Comprehensive Capture and Delineation of Proanthocyanidin Structures[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2020,68(47):13541-13549.
APA	Jing, Shuxi.,Zeller, Wayne E..,Ferreira, Daneel.,Zhou, Bin.,Nam, Joo-Won.,...&Pauli, Guido F..(2020).Proanthocyanidin Block Arrays (PACBAR) for Comprehensive Capture and Delineation of Proanthocyanidin Structures.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,68(47),13541-13549.
MLA	Jing, Shuxi,et al."Proanthocyanidin Block Arrays (PACBAR) for Comprehensive Capture and Delineation of Proanthocyanidin Structures".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 68.47(2020):13541-13549.