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科研机构
上海药物研究所 [218]
内容类型
期刊论文 [213]
会议论文 [5]
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2021 [11]
2020 [14]
2019 [16]
2018 [26]
2017 [16]
2016 [10]
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Chemistry [1]
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Guaianolides from Artemisia codonocephala suppress interleukine-1 beta secretion in macrophages
期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 192, 页码: 10
作者:
Wang, Qiaoqiao
;
Zhang, Tian
;
Ke, Chang-Qiang
;
Tang, Chunping
;
Yao, Sheng
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/12/01
Artemisia codonocephala
Asteraceae
Guaianolides
Anti-inflammation
IL-1 beta
NLRP3
Three new carabrane sesquiterpenoid derivatives from the whole plant of Carpesium abrotanoides L.
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2021, 卷号: 19, 期号: 11, 页码: 868-873
作者:
Wu Jie-Wei
;
Tang Chun-Ping
;
Yao Sheng
;
Ke Chang-Qiang
;
Ye Yang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/01/18
Sesquiterpenoid dimer
Carpesium abrotanoides L.
Carabrane sesquiterpenoid
Dicarabrol B
Dicarabrol C
11R-hydroxycarabrol
Noreudesmane sesquiterpenoids from Artemisia hedinii and their anti-inflammatory activities
期刊论文
FITOTERAPIA, 2021, 卷号: 153, 页码: 9
作者:
Wang, Xing
;
Tang, Chunping
;
Meng, Suoriya
;
Tang, Bixi
;
Zang, Yi
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/11/04
Artemisia hedinii
Sesquiterpenoid
Dinoreudesmane
Trinoreudesmane
Anti-inflammatory activity
Synthesis and Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitory Activity Evaluation of Novel N-Acylhydrazone Derivatives Containing Carbazole and Aromatic Ring/Aromatic Fused Heterocycle
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 9, 页码: 3593-3607
作者:
Li Yingjun
;
Lin Ledi
;
Liu Jihong
;
Gao Lixin
;
Sheng Li
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/12/01
PTP1B inhibitor
carbazole
N-actylhydrazone
synthesis
molecular docking
Enzyme-Activated Prodrug-Based Smart Liposomes Specifically Enhance Tumor Hemoperfusion with Efficient Drug Delivery to Pancreatic Cancer Cells and Stellate Cells
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2021, 页码: 14
作者:
Duan, Nianxiu
;
Li, Junjun
;
Song, Sha
;
Wang, Feng
;
Yang, Yiwei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/11/04
drug delivery
pancreatic cancer
prodrugs
smart liposomes
tumor-specific vascular promotion
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Wang, Lin
;
Wu, Yan
;
Yao, Sheng
;
Ge, Huan
;
Zhu, Ya
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/11/04
SARS-CoV-2
natural products
virtual screening
spike protein
protein-protein interaction modulators
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 7, 页码: 1885-1902
作者:
Wu, Xu
;
Yin, Chun
;
Ma, Jiang
;
Chai, Stella
;
Zhang, Chunyuan
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/11/04
Multidrug resistance
ABCB1
Polyoxypregnane
Combination chemotherapy
Marsdenia tenacissima
Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:
Su, Haixia
;
Yao, Sheng
;
Zhao, Wenfeng
;
Zhang, Yumin
;
Liu, Jia
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/08/17
Anti-inflammatory Eudesmane Sesquiterpenoids from Artemisia hedinii
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 5, 页码: 1626-1637
作者:
Wang, Xing
;
Peng, Xia
;
Tang, Chunping
;
Zhou, Shuaizhen
;
Ke, Chang-Qiang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/08/17
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