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科研机构
中南大学 [5]
内容类型
期刊论文 [5]
发表日期
2018 [1]
2016 [1]
2015 [3]
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专题:中南大学
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Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
The clinicopathological significance of miR-149 and PARP-2 in hepatocellular carcinoma and their roles in chemo/radiotherapy
期刊论文
Tumor Biology, 2016, 卷号: 37, 期号: 9, 页码: 12339-12346
作者:
Lin, Ling
;
Zhang, Yang-de
;
Chen, Zi-yu
;
Chen, Yuxiang*
;
Ren, Cai-ping*
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
Chemotherapy
Hepatocellular carcinoma
PARP-2
Prognosis
Radiotherapy
miR-149
TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1
期刊论文
Oncotarget, 2015, 卷号: 6, 期号: 9, 页码: 7011-7022
作者:
Zou, Lian-Hong
;
Shang, Zeng-Fu
;
Tan, Wei
;
Liu, Xiao-Dan
;
Xu, Qin-Zhi
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
DNA repair
DNA-PKcs
TNKS1BP1
poly(ADP-ribosyl)ation
radiation
Combination of erlotinib and a PARP inhibitor inhibits growth of A2780 tumor xenografts due to increased autophagy
期刊论文
Drug Design, Development and Therapy, 2015, 卷号: 9, 页码: 3183-3190
作者:
Sui, Hongying*
;
Shi, Caixia
;
Yan, Zhipeng
;
Li, Hucheng
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/03
A2780 (EGFR-overexpressing
BRCA1/2 wild-type) cells were subcutaneously injected into nude mice
which were then randomly assigned to treatment with vehicle
erlotinib
AZD2281
or erlotinib + AZD2281
for up to 3 weeks. All mice were then sacrificed and tumor tissues were subjected to Western blot analysis and monodansylcadervarine staining (for analysis of autophagy).
Poly-ADP-ribosylation of HMGB1 regulates TNFSF10/TRAIL resistance through autophagy
期刊论文
Autophagy, 2015, 卷号: 11, 期号: 2, 页码: 214-224
作者:
Yang, Minghua
;
Liu, Liying
;
Xie, Min
;
Sun, Xiaofang
;
Yu, Yan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
Apoptosis
Autophagy
HMGB1
PARP-1
TRAIL
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