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科研机构
上海药物研究所 [69]
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期刊论文 [67]
会议论文 [2]
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2021 [1]
2020 [1]
2019 [2]
2018 [4]
2017 [1]
2016 [1]
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Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo: involvement of the PI3K-AKT-mTOR/JNK pathway
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 卷号: 53, 期号: 5, 页码: 575-583
作者:
Hu, Ke
;
Li, Bo
;
Ma, Ruye
;
Yi, Hongfei
;
Xu, Zhijian
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/06/11
caspase
cell proliferation
cell cycle arrest
diffuse large B-cell lymphoma
PI3K-AKT-mTOR/JNK pathway
A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 11
作者:
Lu, Kang
;
Li, Bo
;
Zhang, Hui
;
Xu, Zhijian
;
Song, Dongliang
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  |  
浏览/下载:57/0
  |  
提交时间:2020/07/01
Evaluation and Simulation Verification of Thermal Insulation Property of Fiber Fabric Materials in Space Environment
期刊论文
JOURNAL OF INORGANIC MATERIALS, 2019, 卷号: 34, 期号: 11, 页码: 1238-1244
作者:
Luo Cai-Yun
;
Yang Li-Ping
;
Tao Ye
;
Zhong Qiu
;
Li Hui-Dong
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
space microgravity environment
fiber fabric insulation material
effective thermal conductivity
steady-state heat flow meter method
temperature field simulation
Simultaneous determination of resibufogenin and its eight metabolites in rat plasma by LC-MS/MS for metabolic profiles and pharmacokinetic study
期刊论文
PHYTOMEDICINE, 2019, 卷号: 60, 页码: 7
作者:
Wei, Wen-long
;
An, Ya-ling
;
Li, Zhen-wei
;
Wang, Ying-ying
;
Ji, Hong-jian
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
Resibufogenin
Metabolites
Quantitation
Pharmacokinetics
Metabolic profiles
Development of an LC-MS/MS-based assay to determine artemitin in rat plasma and its application in a pharmacokinetic study
期刊论文
Biomedical chromatography : BMC, 2018, 卷号: 32, 期号: 12, 页码: e4356
作者:
Han, Xiaoli
;
He, Jinhua
;
Chen, Qinyue
;
Sun, Yali
;
Zhang, Xiulei
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
Rapid, reliable, and sensitive detection of adenosine deaminase activity by UHPLC-Q-Orbitrap HRMS and its application to inhibitory activity evaluation of traditional Chinese medicines
期刊论文
Journal of pharmaceutical and biomedical analysis, 2018, 卷号: 153, 页码: 175-181
作者:
Qi, Shenglan
;
Guan, Huida
;
Deng, Gang
;
Yang, Tao
;
Cheng, Xuemei
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  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Development and validation of a sensitive and rapid UHPLC-MS/MS method for the simultaneous quantification of the common active and inactive metabolites of vicagrel and clopidogrel in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 卷号: 149, 页码: 394-402
作者:
Liu, Cai
;
Lu, Youming
;
Sun, Hongbin
;
Yang, Jin
;
Liu, Yongqiang
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  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Vicagrel
Clopidogrel
Active metabolite
LC-MS/MS
Human plasma
P2Y(12) inhibitor
Simultaneous determination of flavonol glycoside and its major metabolites by LC-MS/MS in rat plasma
期刊论文
Acta Pharmaceutica Sinica, 2018, 卷号: 53, 期号: 8, 页码: 1344-1350
作者:
Dong Lei
;
Liu Jinqiu
;
Li Liang
;
Chen Xiaoyan
;
Shan Weiguang
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  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
LC-MS/MS
flavonol glycoside
glucuronide conjugate
pharmacokinetics
Simultaneous determination of donafenib and its N-oxide metabolite in human plasma by liquid chromatography-tandem mass spectrometry
期刊论文
Acta Pharmaceutica Sinica, 2017, 卷号: 52, 期号: 3, 页码: 443-448
作者:
Wang Jing
;
Lu Binhua
;
Dai Xiaojian
;
Zhang Yifan
;
Chen Xiaoyan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
LC-MS/MS
LC-MS/MS
donafenib
sorafenib
N-oxide metabolite
Absorption mechanism of neobavaisoflavone in Caco-2 cell monolayer mode
期刊论文
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2016, 卷号: 41, 期号: 15, 页码: 2922-2926
作者:
Xu, Xiao-Kun
;
Chen, Zhi-Yong
;
Li, Zhuo-Qing
;
Zhang, Yi-Min
;
Liao, Li-Ping
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  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
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