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科研机构
上海药物研究所 [1434]
内容类型
期刊论文 [1422]
会议论文 [11]
学位论文 [1]
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2021 [83]
2020 [107]
2019 [118]
2018 [163]
2017 [136]
2016 [128]
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学科主题
Pharmacol... [21]
Oncology [17]
Biochemist... [9]
Chemistry [6]
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Enzalutamide-induced and PTH1R-mediated TGFBR2 degradation in osteoblasts confers resistance in prostate cancer bone metastases
期刊论文
CANCER LETTERS, 2022, 卷号: 525, 页码: 170-178
作者:
Su, Shang
;
Cao, Jingchen
;
Meng, Xiangqi
;
Liu, Ruihua
;
Vander Ark, Alexandra
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/01/04
Enzalutamide resistance
Prostate cancer
Bone microenvironment
TGFBR2
PTH1R
Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma
期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:
Chen, Zi-qi
;
Cao, Zhe-rui
;
Wang, Yi
;
Zhang, Xi
;
Xu, Lan
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/12/16
CYH33
MYC
P300
BET
B cell lymphoma
PI3K
The discovery of a novel series of potential ERR alpha inverse agonists based on p-nitrobenzenesulfonamide template for triple-negative breast cancer in vivo
期刊论文
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 125-134
作者:
Gao, Zhipei
;
Wang, Tianxiao
;
Li, Rui
;
Du, Yongli
;
Lv, Han
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/01/18
ERR alpha
TNBC
p-Nitrobenzenesulfonamide
inverse agonist
A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters
期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 13, 期号: 1, 页码: 247-256
作者:
Dong, Lei
;
Zhang, Min-Yu
;
Han, Hai-Hao
;
Zang, Yi
;
Chen, Guo-Rong
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  |  
浏览/下载:31/0
  |  
提交时间:2022/01/18
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14
作者:
Zhang, Chun
;
Sun, Yi-Tao
;
Gao, Li-Xin
;
Feng, Bo
;
Yan, Xue
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/01/18
M2 macrophage microvesicle-inspired nanovehicles improve accessibility to cancer cells and cancer stem cells in tumors
期刊论文
Journal of Nanobiotechnology, 2021, 卷号: 19, 期号: 1
作者:
Wang,Yuqi
;
Gong,Xiang
;
Li,Jie
;
Wang,Hong
;
Xu,Xiaoxuan
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  |  
浏览/下载:44/0
  |  
提交时间:2021/12/16
Cancer stem cells
Macrophage
Microvesicle
Nanoparticles
Cabazitaxel
Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGF beta signaling
期刊论文
ONCOGENE, 2021, 页码: 10
作者:
Kong, Ya
;
Zhang, Yutian
;
Wang, Hanlin
;
Kan, Weijuan
;
Guo, Haoran
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2022/01/04
SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 339, 页码: 297-306
作者:
Huang, Ying
;
Wang, Lei
;
Cheng, Zhiyang
;
Yang, Biyu
;
Yu, Jiahui
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/12/01
Antitumour
Chemotherapy
SN38
Drug delivery systems
Albumin
Combating liver cancer through GO-targeted biomaterials
期刊论文
BIOMEDICAL MATERIALS, 2021, 卷号: 16, 期号: 6, 页码: 14
作者:
Huang, Xing
;
Zhang, Jiaxin
;
Song, Yijie
;
Zhang, Tong
;
Wang, Bing
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/11/04
graphene oxide
hydroxycamptothecin
anti-cancer
drug delivery system
targeting
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