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科研机构
中南大学 [9]
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期刊论文 [9]
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2018 [1]
2016 [3]
2014 [1]
2013 [2]
2012 [1]
2010 [1]
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内容类型:期刊论文
专题:中南大学
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Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
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浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
MDM2 promotes rheumatoid arthritis via activation of MAPK and NF-κB
期刊论文
International Immunopharmacology, 2016, 卷号: 30, 页码: 69-73
作者:
Zhang, Lin
;
Luo, Jing
;
Wen, Hongyan
;
Zhang, Tingting
;
Zuo, Xiaoxia*
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  |  
浏览/下载:1/0
  |  
提交时间:2019/12/03
FLS
MAPK
MDM2
NF-kappaB
Rheumatoid arthritis
MicroRNA-340 inhibits prostate cancer cell proliferation and metastasis by targeting the MDM2-p53 pathway
期刊论文
Oncology Reports, 2016, 卷号: 35, 期号: 2, 页码: 887-895
作者:
Huang, Kai
;
Tang, Yuxin*
;
He, Leye
;
Dai, Yingbo
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  |  
浏览/下载:1/0
  |  
提交时间:2019/12/03
miR-340
prostate cancer
MDM2
p53
microRNAs
Renoprotective approaches and strategies in acute kidney injury
期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 163, 页码: 58-73
作者:
Yang, Yuan
;
Song, Meifang
;
Liu, Yu
;
Liu, Hong
;
Sun, Lin
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/03
ACTH
Adrenocorticotropic hormone
AIF
Apoptosis inducing factor
AKI
Acute kidney injury
BMSC
Bone marrow derived stem cells
CIN
Contrast-induced nephropathy
COMP-Ang1
Cartilage oligomeric matrix protein-angiopoietin-1
CysLT1R
Cysteinyl leukotriene-1 receptor
DMARD
Disease-modifying antirheumatic drugs
eNOS
Endothelial nitric oxide synthase
eEPCs
Endothelial progenitor cells
HDAC
Histone deacetylase
HSPC
Hematopoietic stem and progenitor cells
IRI
Ischemia–reperfusion injury
ICAM-1
Intercellular adhesion molecule-1
JNK
c-Jun N-terminal kinase
KIF3B
Kinesin family member 3B
KIM-1
Kidney injury molecule 1
MAPK
Mitogen-activated protein kinase
MCP-1
Monocyte chemotactic protein-1
α-MSH
Alpha-melanocyte-stimulating hormone
MFG-E8
Milk fat globule-epidermal growth factor-factor VIII
MPT
Mitochondrial permeability transition
MSCs
Mesenchymal stem cells
NGAL
Neutrophil gelatinase-associated lipocalin
MDM2
Murine double minute-2
MMP-2
Matrix metallopeptidase 2
mTOR
Mammalian target of rapamycin
PI3K
Phosphatidylinositol-3 kinase
PACAP
Pituitary adenylate cyclase activating polypeptide
RAAS
Renin–angiotensin–aldosterone system
RANTES
Regulated upon activation normal T-cell expressed and secreted
RIP1
Receptor-interacting protein 1
TNF-α
Tumor necrosis factor-alpha
TWEAK
TNF-like weak inducer of apoptosis
VDRA
Vitamin D receptor agonist
Acute kidney injury
Kidney protection
Kidney repair
Renoprotection
Ischemia–reperfusion
Nephrotoxicity
DNAJB1 stabilizes MDM2 and contributes to cancer cell proliferation in a p53-dependent manner
期刊论文
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2014, 卷号: 1839, 期号: 1, 页码: 62-69
作者:
Qi, Min
;
Zhang, Jianglin
;
Zeng, Weiqi*
;
Chen, Xiang
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  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
DNAJB1
MDM2
p53
p21
HSP70
Association analysis between genetic variants of MDM2 gene and osteosarcoma susceptibility in Chinese
期刊论文
Endocrine Journal, 2013, 卷号: 60, 期号: 11, 页码: 1215-1220
作者:
He, Jinshan
;
Wane, Jingcheng
;
Wane, Daxin
;
Dail, Shanhe
;
Yvl, Tangyan
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
Osteosarcoma
MDM2 gene
Genetic variants
Molecular markers
Susceptibility
Epigallocatechin gallate promotes p53 accumulation and activity via the inhibition of MDM2-mediated p53 ubiquitination in human lung cancer cells
期刊论文
Oncology Reports, 2013, 卷号: 29, 期号: 5, 页码: 1983-1990
作者:
Jin, Longyu
;
Li, Cui
;
Xu, Yan
;
Wang, Li
;
Liu, Jianxin
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/03
Anchorage-independent growth
Epigallocatechin gallate
MDM2
p53
Inauhzin and Nutlin3 synergistically activate p53 and suppress tumor growth
期刊论文
Cancer Biology and Therapy, 2012, 卷号: 13, 期号: 10, 页码: 915-924
作者:
Zhang, Yiwei
;
Zhang, Qi
;
Zeng, Shelya X.
;
Zhang, Yu
;
Mayo, Lindsey D.
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
inauhzin
Nutlin-3
p53
small molecule inhibitor
apoptosis
xenograft tumor
acetylation
deacetylation
MDM2
The Tumor Suppressor UCHL1 Forms a Complex with p53/MDM2/ARF to Promote p53 Signaling and Is Frequently Silenced in Nasopharyngeal Carcinoma
期刊论文
Clinical Cancer Research, 2010, 卷号: 16, 期号: 11, 页码: 2949-2958
作者:
Lili Li
;
Qian Tao
;
Hongchuan Jin
;
Andrew van Hasselt
;
Fan Fong Poon
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/03
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