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浏览/检索结果: 共6条，第1-6条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A near-infrared fluorescent probe was used to evaluate the role of histone deacetylase in pulmonary fibrosis cells and mice 期刊论文 SENSORS AND ACTUATORS B-CHEMICAL, 2022, 卷号: 366, 页码: 8 作者:  Wei, Yinghui;  Hou, Junjun;  Lu, Pengpeng;  Fu, Lili;  Wang, Xiaoyan 收藏  |  浏览/下载：34/0  |  提交时间：2022/07/26 Fluorescent probe  Near-infrared  Histone deacetylases  Idiopathic pulmonary fibrosis  Fluorescence imaging   Terpyridine Zn(II) Complexes with Azide Units for Visualization of Histone Deacetylation in Living Cells under STED Nanoscopy 期刊论文 ACS SENSORS, 2021, 卷号: 6 作者:  Du, Wei;  Pan, Dayi;  Xiang, Pan;  Xiong, Chaoya;  Zhang, Mingzhu 收藏  |  浏览/下载：44/0  |  提交时间：2022/03/21 Zn complexes  azide units  histone probe  STED nanoscopy  super-resolution imaging   Development of a Novel Histone Deacetylase-Targeted Near-Infrared Probe for Hepatocellular Carcinoma Imaging and Fluorescence Image-Guided Surgery 期刊论文 MOLECULAR IMAGING AND BIOLOGY, 2020, 卷号: 22, 期号: 3, 页码: 476-485 作者:  Tang, Chu;  Du, Yang;  Liang, Qian;  Cheng, Zhen;  Tian, Jie 收藏  |  浏览/下载：20/0  |  提交时间：2020/06/22 Specific targeting probe  Histone deacetylase  Fluorescence imaging  Hepatocellular carcinoma  Fluorescence image-guided surgery   Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10 作者:  Hou, Zeng;  Min, Wenjian;  Zhang, Rukang;  Niu, Ao;  Li, Yuanqing 收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01 Histone methylation  SET7  Small-molecule inhibitor  Virtual screening  Molecular probe   Epigenetic targets and drug discovery Part 2: Histone demethylation and DNA methylation 期刊论文 Pharmacology and Therapeutics, 2015, 卷号: 151, 页码: 121-140 作者:  Liu, Ke;  Liu, Yanli;  Lau, Johnathan L;  Min, Jinrong* 收藏  |  浏览/下载：13/0  |  提交时间：2019/12/23 Histone demethylation  DNA methylation  Inhibitor  Chemical probe  Drug discovery  LSD  lysine-specific histone demethylase  HDAC  histone deacetylase  REST  REST corepressor  DNMT  DNA methyltransferase  MAO  monoamine oxidase  AML  acute myeloid leukemia  KDM  lysine-specific demethylase  MLL  mixed lineage leukemia  FAD  flavin adenine dinucleotide  PCPA  trans-2-phenylcyclopropylamine  2,4-PDCA  2, 4-pyridinedicarboxylic acid  PHD  plant homeobox domain  SCLC  small cell lung cancer  JHDMs  JmjC-domain-containing histone demethylases  NOG  N-oxalylglycine  IOX1  5-carboxy-8-hydroxyquinoline  MDS  myelodysplastic syndrome  2-OG, 2-oxoglutarate or  α-ketoglutarate  G9a  euchromatic histone-lysine N-methyltransferase 2  CoREST complex  restin corepressor complex  SAH  S-adenosyl-l-homocysteine  l  SWI complex  ATP dependent chromatin remodeling complexes  Pan-Histone Demethylase Inhibitor  the inhibitor can simultaneously inhibit both LSDs and JHDMs  LSC colony  leukemic stem cell colony  Pan JmjC domain-containing demethylase inhibitor  the inhibitor can simultaneously inhibit all the members of JHDMs  E2F1  E2F transcription factor 1  E2F2  E2F transcription factor 2  RCC  renal cell carcinoma   Epigenetic targets and drug discovery: Part 1: Histone methylation 期刊论文 Pharmacology and Therapeutics, 2014, 卷号: 143, 期号: 3, 页码: 275-294 作者:  Liu, Yanli;  Liu, Ke;  Qin, Su;  Xu, Chao;  Min, Jinrong* 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/23 Epigenetics  Histone methylation  Inhibitor  Chemical probe  Cancer  PTM  posttranslational modification  HMTs  histone methyltrans-ferases  SET  Suv39, E(z) and Trithorax  SUV39  Su(var)3-9  SUV420  histone-lysine N-methyltransferase SUV420  G9a  euchromatic histone-lysine N-methyltransferase 2  GLP  G9a-like protein 1  Wiz  widely-interspaced zinc finger-containing protein  CDYL1  chromodomain Y-like protein  ACIN1  apoptotic chromatin condensation inducer in the nucleus  SAH  S-adenosyl-l-homocysteine  l  SAM  S-adenosylmethionine  Dot1  disruptor of telomeric silencing  Dot1L  DOT1-Like protein  EZH1  Enhancer of zeste homolog 1  EZH2  Enhancer of zeste homolog 2  Hox  homeotic box  PcG  Polycomb group  PRC1  Polycomb Repressive Complex 1  PRC2  Polycomb Repressive Complex 2  DZNep  3-Deazan- eplanocin A  SMYD2  SET and MYND domain-containing protein 2  PRMT  protein arginine methyltransferases  AMI-1  arginine methyltransferase inhibitor-1  MBT  Malignant Brain Tumor  PEV  position-effect variegation  HSPC  hematopoietic stem and progenitor cells  ChIP  chromatin immunoprecipitation  PK  pharmacokinetic