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CORC

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Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists 期刊论文
PHARMACEUTICALS, 2022, 卷号: 15
作者:  Sun, Lei;  Zheng, Zhi-Ming;  Shao, Chang-Sheng;  Zhang, Zhi-Yong;  Li, Ming-Wei
收藏  |  浏览/下载：16/0  |  提交时间：2022/12/22
The discovery of a novel series of potential ERR alpha inverse agonists based on p-nitrobenzenesulfonamide template for triple-negative breast cancer in vivo 期刊论文
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 125-134
作者:  Gao, Zhipei;  Wang, Tianxiao;  Li, Rui;  Du, Yongli;  Lv, Han
收藏  |  浏览/下载：40/0  |  提交时间：2022/01/18
Novel selective kappa agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Wei, Yuan-yuan;  Ma, Yan;  Yao, Song-yu;  Kong, Ling-hui;  Liu, Xiao
收藏  |  浏览/下载：40/0  |  提交时间：2021/11/04
Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 43, 页码: 13
作者:  Tang, Xuehang;  Ning, Mengmeng;  Ye, Yangliang;  Gu, Yipei;  Yan, Hongyi
收藏  |  浏览/下载：49/0  |  提交时间：2021/11/04
Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 17
作者:  Lin, Lin;  Lin, Guangyao;  Zhou, Qingtong;  Bathgate, Ross A. D.;  Gong, Grace Qun
收藏  |  浏览/下载：31/0  |  提交时间：2021/08/17
A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation 期刊论文
LIFE SCIENCES, 2021, 卷号: 269, 页码: 8
作者:  Yang, Liu;  Lei, Xian-Tao;  Huang, Qi;  Wang, Ting;  Sun, Hong-Bin
收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24
Tracking Response Dynamics of Sequential Working Memory in Patients With Mild Parkinson's Disease 期刊论文
FRONTIERS IN PSYCHOLOGY, 2021, 卷号: 12, 页码: 8
作者:  Zhang, Guanyu;  Ma, Jinghong;  Chan, Piu;  Ye, Zheng
收藏  |  浏览/下载：61/0  |  提交时间：2021/04/01
Design, Synthesis, and Structure-Activity Relationship Exploration of Alkyl/Phenylalkyl Piperidine Analogues as Novel Highly Potent and Selective mu Opioid Receptor Agonists 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 2, 页码: 285-299
作者:  Huang, Huoming;  Li, Xinwei;  Guo, Wei;  Zhu, Chen;  Qian, Yuanyuan
收藏  |  浏览/下载：26/0  |  提交时间：2021/05/24
Sanguinarine is an agonist of TRPA1 channel 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021, 卷号: 534, 页码: 226-232
作者:  Chi, Hao;  Zhang, Xian;  Chen, Xueqin;  Fang, Sui;  Ding, Qiang
收藏  |  浏览/下载：17/0  |  提交时间：2021/05/24
Insights into the molecular mechanism of positive cooperativity between partial agonist MK-8666 and full allosteric agonist AP8 of hGPR40 by Gaussian accelerated molecular dynamics (GaMD) simulations 期刊论文
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 页码: 3978-3989
作者:  An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Liu, Huanxiang;  Yao, Xiaojun
收藏  |  浏览/下载：13/0  |  提交时间：2021/12/08

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