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科研机构
北京大学 [3]
四川大学 [2]
中南大学 [2]
厦门大学 [1]
内容类型
期刊论文 [8]
发表日期
2018 [3]
2017 [1]
2011 [1]
2004 [1]
2003 [1]
2000 [1]
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Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Molecular Mechanism of Different Signaling Pathways in Regulating PD-L1 Expression in EGFR Mutated Lung Adenocarcinoma
期刊论文
Chinese Journal of Lung Cancer, 2018, 卷号: Vol.21 No.11, 页码: 875-879
作者:
Xuefeng LENG
;
Jiandong MEI
;
Lunxu LIU
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/02/25
Epidermal
growth
factor
receptor
Programmed
death
ligand
1
Signaling
pathways
Lung
neoplasms
Molecular Mechanism of Different Signaling Pathways in Regulating PD-L1 Expression in EGFR Mutated Lung Adenocarcinoma
期刊论文
Chinese Journal of Lung Cancer, 2018, 卷号: Vol.21 No.11, 页码: 875-879
作者:
Xuefeng LENG
;
Jiandong MEI
;
Lunxu LIU
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/02/25
Epidermal
growth
factor
receptor
Programmed
death
ligand
1
Signaling
pathways
Lung
neoplasms
IL-9 and Th9 cells in health and diseases—From tolerance to immunopathology
期刊论文
Cytokine and Growth Factor Reviews, 2017, 卷号: 37, 页码: 47-55
作者:
Li, Junhui
;
Chen, Shuqiu
;
Xiao, Xiang
;
Zhao, Yong
;
Ding, Wenjun
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/03
TNFRSF
Tumor necrosis factor receptor super family
GITR
Glucocorticoid-induced tumor necrosis factor receptor
DR3
Death receptor 3
ILC2
Type II innate lymph cells
CNS
Conserved non-coding sequences
TSS
Transcription start site
TCR
T cell receptor
NICD
Notch intracellular domain
CIS
Cytokine-induced SH-2
SOCS
Suppressor of cytokine signaling
NIK
NF-Kb inducing kinase
TL1A
TNF-like ligand 1A
IBD
Inflammatory bowel diseases
MS
Multiple sclerosis
SLE
Systemic lupus erythematosus
RA
Rheumatic arthritis
EAE
Experimental autoimmune encephalomyelitis
MOG
Myelin oligodendrocyte glycoprotein
IRF4
IFN-regulation factor 4
mAb
Monoclonal antibody
Th9
Transcription mechanism
Immunity and immunopathology
Therapeutic purposes
Triggering of death receptor apoptotic signaling by human papillomavirus 16 E2 protein in cervical cancer cell lines is mediated by interaction with c-FLIP
期刊论文
2011
方亚
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2013/12/12
HPV E2
Apoptosis
cFLIP
Death receptor signaling
Cervical carcinogenesis
Identification of a ZU5 and death domain-containing inhibitor of NF-kappa B
期刊论文
journal of biological chemistry, 2004
Zhang, J
;
Xu, LG
;
Han, KJ
;
Shu, HB
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/16
TNF RECEPTOR
CELL-DEATH
TRANSCRIPTIONAL ACTIVITY
SIGNALING COMPLEX
PROTEIN
ACTIVATION
APOPTOSIS
RIP
INTERACTS
FADD
SINK is a p65-interacting negative regulator of NF-kappa B-dependent transcription
期刊论文
journal of biological chemistry, 2003
Wu, M
;
Xu, LG
;
Zhai, ZH
;
Shu, HB
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/14
NECROSIS-FACTOR FAMILY
TNF RECEPTOR
SIGNALING COMPLEX
MEMBER TALL-1
CELL-DEATH
IKK-GAMMA
ACTIVATION
PROTEIN
KINASE
IDENTIFICATION
Activation of NF-kappa B by FADD, Casper, and caspase-8
期刊论文
journal of biological chemistry, 2000
Hu, WH
;
Johnson, H
;
Shu, HB
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/16
NECROSIS-FACTOR RECEPTOR
1-ASSOCIATED PROTEIN TRADD
DOMAIN-CONTAINING PROTEIN
INDUCED CELL-DEATH
INDUCED APOPTOSIS
SIGNALING COMPLEX
CD95 FAS/APO-1
KINASE RIP
TNF
ALPHA
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