apoptosis  Bax  cell proliferation  c-Jun  Claudin-15  nerve regeneration  peripheral nerve injury  protein kinase C alpha  Schwann cells  Wallerian degeneration  

endoplasmic reticulum stress (ER stress)  calcium intracellular release  apoptosis  zebrafish  stress response  apoptosis  calcium homeostasis  cold exposure  endoplasmic reticulum stress  calcium homeostasis  Grinaa  transmembrane BAX inhibitor motif (TMBIM)  unfolded protein response (UPR)  cell death  

ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  

T-2/HT-2 toxin  Cytotoxicity  Apoptosis  Liver toxicity  Hepatocytes  T-2  T-2 toxin  HT-2  HT-2 toxin  Bcl-2  B-cell lymphoma 2  Bax  Bcl-2 Associated X protein  MTT  3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide  TUNEL  Terminal transferase nick-end labeling  ALT  alanine aminotransferase  AST  aspartate aminotransferase  PCR  polymerase chain reaction  DMEM  Dulbecco's modified Eagle's medium  D-HBSS  D-Hank's balanced salt solution  DMSO  dimethyl sulfoxide  FITC  Fluorescein Isothiocyanate  PI  Propidium Iodide  T-TBS  Tris Buffered Saline−Tween  S.E.  standard error of measurement  PVDF  polyvinylidene fluoride  T-TBS  Tris Buffered Saline−Tween  

B-cell lymphoma 2 (Bcl-2)  Bax  Bcl2  cyathane diterpenoid  mitochondrial apoptosis  oligomerization  protein cross-linking  voltage-dependent anion channel (VDAC)