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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance (vol 19, 90, 2020)
期刊论文
MOLECULAR CANCER, 2021, 卷号: 20, 期号: 1, 页码: 1
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/04
Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
Molecular Cancer, 2021, 卷号: 20, 期号: 1
作者:
Zhang,Tao
;
Qu,Rong
;
Chan,Shingpan
;
Lai,Mengzhen
;
Tong,Linjiang
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/11/04
D-0316 in patients with advanced T790M-positive EGFR-mutant non-small cell lung cancer who progressed on prior EGFR-TKI therapy: results from a phase II study (NCT03861156).
期刊论文
CANCER RESEARCH, 2021, 卷号: 81
作者:
Lu, Shun
;
Zhang, Yiping
;
Zhang, Guojun
;
Zhou, Jianying
;
Cang, Shundong
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  |  
浏览/下载:58/0
  |  
提交时间:2021/11/01
Feasibility and physics potential of detecting 8B solar neutrinos at JUNO * * This work was supported by the Chinese Academy of Sciences, the National Key R&D Program of China, the CAS Center for Excellence in Particle Physics, the Joint Large-Scale Scientific Facility Funds of the NSFC and CAS, Wuyi University, and the Tsung-Dao Lee Institute of Shanghai Jiao Tong University in China, the Institut National de Physique Nucléaire et de Physique de Particules (IN2P3) in France, the Istituto Nazionale di Fisica Nucleare (INFN) in Italy, the Fond de la Recherche Scientifique (F.R.S-FNRS) and FWO under the “Excellence of Science – EOS” in Belgium, the Conselho Nacional de Desenvolvimento Científico e Tecnològico in Brazil, the Agencia Nacional de Investigación y Desarrollo in Chile, the Charles University Research Centre and the Ministry of Education, Youth, and Sports in Czech Republic, the Deutsche Forschungsgemeinschaft (DFG), the Helmholtz Association, and the Cluster of Excellence PRISMA+ in Germany, the Joint Institute of Nuclear Research (JINR), Lomonosov Moscow State University, and Russian Foundation for Basic Research (RFBR) in Russia, the MOST and MOE in Taiwan, the Chulalongkorn University and Suranaree University of Technology in Thailand, and the University of California at Irvine in USA
期刊论文
Chinese Physics C, 2021, 卷号: 45, 期号: 2
作者:
Abusleme,Angel
;
Adam,Thomas
;
Ahmad,Shakeel
;
Aiello,Sebastiano
;
Akram,Muhammad
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  |  
浏览/下载:70/0
  |  
提交时间:2021/12/10
neutrino oscillation
solar neutrino
JUNO
Feasibility and physics potential of detecting 8B solar neutrinos at JUNO * * This work was supported by the Chinese Academy of Sciences, the National Key R&D Program of China, the CAS Center for Excellence in Particle Physics, the Joint Large-Scale Scientific Facility Funds of the NSFC and CAS, Wuyi University, and the Tsung-Dao Lee Institute of Shanghai Jiao Tong University in China, the Institut National de Physique Nucléaire et de Physique de Particules (IN2P3) in France, the Istituto Nazionale di Fisica Nucleare (INFN) in Italy, the Fond de la Recherche Scientifique (F.R.S-FNRS) and FWO under the “Excellence of Science – EOS” in Belgium, the Conselho Nacional de Desenvolvimento Científico e Tecnològico in Brazil, the Agencia Nacional de Investigación y Desarrollo in Chile, the Charles University Research Centre and the Ministry of Education, Youth, and Sports in Czech Republic, the Deutsche Forschungsgemeinschaft (DFG), the Helmholtz Association, and the Cluster of Excellence PRISMA+ in Germany, the Joint Institute of Nuclear Research (JINR), Lomonosov Moscow State University, and Russian Foundation for Basic Research (RFBR) in Russia, the MOST and MOE in Taiwan, the Chulalongkorn University and Suranaree University of Technology in Thailand, and the University of California at Irvine in USA
期刊论文
Chinese Physics C, 2021, 卷号: 45, 期号: 2
作者:
Abusleme,Angel
;
Adam,Thomas
;
Ahmad,Shakeel
;
Aiello,Sebastiano
;
Akram,Muhammad
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/04/11
neutrino oscillation
solar neutrino
JUNO
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
期刊论文
AUTOPHAGY, 2021, 卷号: 17
作者:
Klionsky, Daniel J.
;
Abdel-Aziz, Amal Kamal
;
Abdelfatah, Sara
;
Abdellatif, Mahmoud
;
Abdoli, Asghar
收藏
  |  
浏览/下载:267/0
  |  
提交时间:2021/05/31
Autophagosome
cancer
flux
LC3
lysosome
macroautophagy
neurodegeneration
phagophore
stress
vacuole
Strain-engineering on GeSe: Raman spectroscopy study†
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 卷号: 23, 期号: 47, 页码: 26997-27004
作者:
Wang, Jin-Jin
;
Zhao, Yi-Feng
;
Zheng, Jun-Ding
;
Wang, Xiao-Ting
;
Deng, Xing
;
Guan, Zhao
;
Ma, Ru-Ru
;
Zhong, Ni
;
Yue, Fang-Yu
;
Wei, Zhong-Ming
;
Xiang, Ping-Hua
;
Duan, Chun-Gang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/03/23
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer (NSCLC)
EGFR T790M
Small-molecule inhibitor
Drug resistance
Ack1
Per- and polyfluoroalkyl substances display structure-dependent inhibition towards UDP-glucuronosyltransferases
期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 254, 页码: -
作者:
Liu, Yong-Zhe
;
Zhang, Zhi-Peng
;
Fu, Zhi-Wei
;
Yang, Kun
;
Ding, Ning
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  |  
浏览/下载:13/0
  |  
提交时间:2020/09/10
Per- and polyfluoroalkyl substances (PFASs)
UDP-Glucuronosyltransferases (UGTs)
Half inhibition concentration (IC50)
Inhibition type
Inhibition kinetic parameters (Ki)
In vitro-in vivo extrapolation (IVIVE)
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