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复旦大学上海医学院 [10]
厦门大学 [5]
上海药物研究所 [4]
中南大学 [3]
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期刊论文 [46]
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Prodrug nanoparticles rationally integrating stroma modification and chemotherapy to treat metastatic pancreatic cancer
期刊论文
BIOMATERIALS, 2021, 卷号: 278
作者:
Wang, Liying
;
Liu, Zimo
;
Zhou, Quan
;
Gu, Sufang
;
Liu, Xiangsheng
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/11/29
Pancreatic cancer
Polymeric prodrug
Calcipotriol
Cancer-associated fibroblast
Metastasis
Cancer-Associated Fibroblast-Derived Interleukin-8 Promotes Ovarian Cancer Cell Stemness and Malignancy Through the Notch3-Mediated Signaling
期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9
作者:
Ji, Zhaodong
;
Tian, Wenjuan
;
Gao, Wen
;
Zang, Rongyu
;
Wang, Huaying
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/08/30
IL-8
tumor stemness
epithelial ovarian cancer
cancer-associated ovarian fibroblasts
Notch3 signal pathway
Stiffness heterogeneity-induced double-edged sword behaviors of carcinoma-associated fibroblasts in antitumor therapy
期刊论文
2019, 卷号: 62, 期号: 6, 页码: 873-884
作者:
Feng, Jiantao
;
Sharma, Shivani
;
Rao, Elizabeth
;
Li, Xiang
;
Zhang, Qiang
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
stiffness
carcinoma-associated fibroblast
tumor microenvironment
chemotherapy
atomic force microscopy
c11anovelfibroblastgrowthfactorreceptor1fgfr1inhibitorsuppressesbreastcancermetastasisandangiogenesis
期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 6, 页码: 823
作者:
Chen Zhuo
;
Tong Linjiang
;
Tang Baiyou
;
Liu Hongyan
;
Wang Xin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
SELECTIVE INHIBITOR
THERAPEUTIC TARGET
DISCOVERY
ACTIVATION
EXPRESSION
PATHWAY
POTENT
C11
FGFR1 inhibitor
antitumor
breast cancer
metastasis
angiogenesis
C11, a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor, suppresses breast cancer metastasis and angiogenesis
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Chen, Zhuo
;
Tong, Lin-Jiang
;
Tang, Bai-You
;
Liu, Hong-Yan
;
Wang, Xin
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2019/01/08
Fibroblast Growth Factor 2 Modulates Hippocampal Microglia Activation in a Neuroinflammation Induced Model of Depression
期刊论文
FRONTIERS IN CELLULAR NEUROSCIENCE, 2018, 卷号: 12, 页码: 14
作者:
Tang, Ming-ming
;
Lin, Wen-juan
;
Pan, Yu-qin
;
Li, Ying-cong
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2018/09/10
Fibroblast Growth Factor 2
Microglia
Depressive-like Behavior
Neuroinflammation
Cytokines
Cx3cl1
Hippocampus
FOXQ1/NDRG1 axis exacerbates hepatocellular carcinoma initiation via enhancing crosstalk between fibroblasts and tumor cells
期刊论文
CANCER LETTERS, 2018, 卷号: 417
作者:
Luo, Qin
;
Wang, Chao-Qun
;
Yang, Lu-Yu
;
Gao, Xiao-Mei
;
Sun, Hao-Ting
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Hepatocellular carcinoma
Cancer associated fibroblast
Initiation
Forkhead box Q1
N-myc downstream-regulated gene 1
The impact of cancer-associated fibroblasts on major hallmarks of pancreatic cancer
期刊论文
THERANOSTICS, 2018, 卷号: 8, 期号: 18
作者:
Sun, Qiqing
;
Zhang, Bo
;
Hu, Qiangsheng
;
Qin, Yi
;
Xu, Wenyan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/05
pancreatic cancer
tumor microenvironment
hallmarks of cancer
cancer-associated fibroblast
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Molecular mechanism of gd@c-82(oh)(22) increasing collagen expression: implication for encaging tumor
期刊论文
Biomaterials, 2018, 卷号: 152, 页码: 24-36
作者:
Liu, Jing
;
Kang, Seung-gu
;
Wang, Peng
;
Wang, Yue
;
Lv, Xiaonan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/04/23
Cancer therapeutics
Fibrosarcoma cells
Molecular dynamics
Gd-metallofullerenol
Tnf receptors
Caging cancer cells
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