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浏览/检索结果: 共8条，第1-8条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文 PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664 作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin 收藏  |  浏览/下载：37/0  |  提交时间：2021/12/01 IDH1-R132H inhibitors  synthesis  biological activity  docking  3-(indol-3-yl)-4-(pyrazolo-[3  4-c]pyridazin-3-yl)-maleimides   Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening 期刊论文 FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11 作者:  Wang, Yuwei;  Tang, Shuai;  Lai, Huanling 收藏  |  浏览/下载：49/0  |  提交时间：2020/12/24 IDH1  gliomas  molecular docking  virtual screening  docking-based virtual screening   Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13 作者:  Wang, Zheng;  Li, Zeng-xia;  Zhao, Wen-cao;  Huang, Hong-bo;  Wang, Jia-qi 收藏  |  浏览/下载：82/0  |  提交时间：2020/12/24 grincamycin B  marine natural product  isocitrate dehydrogenase 1  apoptosis  ER stress  intracellular ROS  Zebrafish embryos  hematological malignancies   Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants 期刊论文 CANCER SCIENCE, 2019, 页码: 9 作者:  Gao, Mingzhao;  Zhu, Hongmei;  Fu, Li;  Li, Yun;  Bao, Xubin 收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01 AG-221  IDH2  leukemia  R140Q  R172K   Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236 作者:  Duan, Zhe;  Liu, Jingqiu;  Niu, Liping;  Wang, Jun;  Feng, Mingqian 收藏  |  浏览/下载：55/0  |  提交时间：2020/07/01 IDH1 mutation  High-throughput screening  Pan-inhibitor  2-HG  Gliomas   Synthesis and biological evaluation of 3-aryl-4-indolyl-maleimides as potent mutant isocitrate dehydrogenase-1 inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 4, 页码: 589-603 作者:  Liu, Xiaoqi;  Hu, Yuanyuan;  Gao, Anhui;  Xu, Meng;  Gao, Lixin 收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01 3-Aryl-4-indolyl-maleimides  IDH1/R132H inhibitors  Tumor 2-HG  Synthesis   3-(7-Azaindolyl)-4-indolylmaleimides as a novel class of mutant isocitrate dehydrogenase-1 inhibitors: Design, synthesis, and biological evaluation 期刊论文 ARCHIV DER PHARMAZIE, 2018, 卷号: 351, 期号: 10 作者:  Hu, Yuanyuan;  Gao, Anhui;  Liao, Honghui;  Zhang, Mengmeng;  Xu, Gaoya 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 2-hydroxyglutaric acid  3-(7-azaindoyl)-4-indolylmaleimides  isocitrate dehydrogenase 1 inhibitors  tumor   3D-QSAR and docking studies on 1-hydroxypyridin-2-one compounds as mutant isocitrate dehydrogenase 1 inhibitors 期刊论文 2016, 卷号: 1123, 页码: 335 作者:  Wang, Zhenya[1];  Chang, Yiqun[1];  Han, Yushui[1];  Liu, Kangjia[1];  Hou, Jinsong[1] 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/06