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Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists 期刊论文
PHARMACEUTICALS, 2022, 卷号: 15
作者:  Sun, Lei;  Zheng, Zhi-Ming;  Shao, Chang-Sheng;  Zhang, Zhi-Yong;  Li, Ming-Wei
收藏  |  浏览/下载:16/0  |  提交时间:2022/12/22
Signaling profiles in HEK 293T cells co-expressing GLP-1 and GIP receptors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 8
作者:  Wang, Yu-zhe;  Yang, De-hua;  Wang, Ming-wei
收藏  |  浏览/下载:22/0  |  提交时间:2021/11/04
Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14
作者:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton
收藏  |  浏览/下载:41/0  |  提交时间:2021/08/17
Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:  Cong, Zhaotong;  Chen, Li-Nan;  Ma, Honglei;  Zhou, Qingtong;  Zou, Xinyu
收藏  |  浏览/下载:46/0  |  提交时间:2021/08/17
Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 180, 页码: 16
作者:  Darbalaei, Sanaz;  Yuliantie, Elita;  Dai, Antao;  Chang, Rulue;  Zhao, Peishen
收藏  |  浏览/下载:19/0  |  提交时间:2020/12/21
Structural insights into the activation of GLP-1R by a small molecule agonist 期刊论文
CELL RESEARCH, 2020, 页码: 3
作者:  Ma, Honglei;  Huang, Wei;  Wang, Xiaoxi;  Zhao, Lihua;  Jiang, Yi
收藏  |  浏览/下载:38/0  |  提交时间:2020/12/24
Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325
作者:  Chang, Rulue;  Zhang, Xin;  Qiao, Anna;  Dai, Antao;  Belousoff, Matthew J.
收藏  |  浏览/下载:86/0  |  提交时间:2020/12/24
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 13
作者:  Yuliantie, Elita;  Darbalaei, Sanaz;  Dai, Antao;  Zhao, Peishen;  Yang, Dehua
收藏  |  浏览/下载:22/0  |  提交时间:2020/12/24
Activation of the GLP-1 receptor by a non-peptidic agonist 期刊论文
NATURE, 2020, 页码: 432-+
作者:  Zhao, Peishen;  Liang, Yi-Lynn;  Belousoff, Matthew J.;  Deganutti, Giuseppe;  Fletcher, Madeleine M.
收藏  |  浏览/下载:33/0  |  提交时间:2020/07/01
Full-length human GLP-1 receptor structure without orthosteric ligands 期刊论文
naturecommunications, 2020, 卷号: 11, 期号: 1, 页码: 1
作者:  Fan Wu;  Linlin Yang;  Kaini Hang;  Mette Laursen;  Lijie Wu
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/01


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