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科研机构
上海药物研究所 [7]
高能物理研究所 [7]
北京大学 [5]
清华大学 [1]
烟台海岸带研究所 [1]
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期刊论文 [21]
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2021 [1]
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浏览/检索结果:
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Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:
Cong, Zhaotong
;
Chen, Li-Nan
;
Ma, Honglei
;
Zhou, Qingtong
;
Zou, Xinyu
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/08/17
Identification and structural insight of an effective PPAR gamma modulator with improved therapeutic index for anti-diabetic drug discovery
期刊论文
CHEMICAL SCIENCE, 2020, 卷号: 11, 期号: 8, 页码: 2260-2268
作者:
Jiang, Haowen
;
Zhou, X. Edward
;
Shi, Jingjing
;
Zhou, Zhi
;
Zhao, Guanguan
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  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Identification of Cbp1, a c-di-GMP Binding Chemoreceptor in Azorhizobium caulinodans ORS571 Involved in Chemotaxis and Nodulation of the Host Plant
期刊论文
FRONTIERS IN MICROBIOLOGY, 2019, 卷号: 10, 页码: 638
作者:
Sun, Y
;
Xie, ZH
;
Sui, F
;
Liu, XL
;
Cheng, WZ
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/08
c-di-GMP
PilZ domain
chemoreceptor
chemotaxis
nodulation
Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK)
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 44, 页码: 16994-17007
作者:
Gu, Xin
;
Bridges, Michael D.
;
Yan, Yan
;
de Waal, Parker W.
;
Zhou, X. Edward
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/01/08
AMP-activated kinase (AMPK)
biophysics
diabetes
metabolic regulation
cancer
ADaM site
DEER
Synthesis and Biological Activities of Novel Small-molecule GLP-1 Receptor Allosteric Regulators
期刊论文
Chinese Journal of Synthetic Chemistry, 2018, 卷号: 26, 期号: 8, 页码: 545-556
作者:
Wang Lei
;
Guo Bin
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  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
GLP-1 receptor
allosteric modulator
indolopyridone
synthesis
structure activity relationship
Mechanism of the allosteric regulation of streptococcus mutans 2 '-deoxycytidylate deaminase
期刊论文
Acta crystallographica section d-structural biology, 2016, 卷号: 72, 期号: 7, 页码: 883-891
作者:
Li, Yanhua
;
Guo, Zhen
;
Jin, Li
;
Wang, Deqiang
;
Gao, Zengqiang
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2019/04/23
Allosteric regulation
Crystal structure
Enzyme inactivation
Enzyme mechanism
Enzyme structure
2 '-deoxycytidylate deaminase
Streptococcus mutans
Mechanism of the allosteric regulation of Streptococcus mutans 2 '-deoxycytidylate deaminase
期刊论文
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2016
Li, Yanhua
;
Guo, Zhen
;
Jin, Li
;
Wang, Deqiang
;
Gao, Zengqiang
;
Su, Xiaodong
;
Hou, Haifeng
;
Dong, Yuhui
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/04
allosteric regulation
crystal structure
enzyme inactivation
enzyme mechanism
enzyme structure
2 &apos
Streptococcus mutans
HUMAN DEOXYCYTIDYLATE DEAMINASE
HEPATITIS-B-VIRUS
CYTIDINE DEAMINASE
CRYSTAL-STRUCTURE
DNTP POOLS
SUBSTRATE
INHIBITOR
SUBUNIT
COMPLEX
BINDING
-deoxycytidylate deaminase
Mechanism of the allosteric regulation of Streptococcus mutans 2 '-deoxycytidylate deaminase
期刊论文
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2016, 卷号: 72, 期号: 7, 页码: 883-891
作者:
Guo, Z
;
Dong YH(董宇辉)
;
Dong, YH
;
Hou, HF
;
Li YH(李艳华)
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/10/12
allosteric regulation
crystal structure
enzyme inactivation
enzyme mechanism
enzyme structure
2 '-deoxycytidylate deaminase
Streptococcus mutans
Mechanism of the allosteric regulation of Streptococcus mutans 2 '-deoxycytidylate deaminase
期刊论文
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2016, 卷号: 72, 期号: 7, 页码: 883-891
作者:
Gao ZQ(高增强)
;
Li, YH
;
Li YH(李艳华)
;
Dong YH(董宇辉)
;
Dong, YH
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/10/12
allosteric regulation
crystal structure
enzyme inactivation
enzyme mechanism
enzyme structure
2 '-deoxycytidylate deaminase
Streptococcus mutans
Mechanism of the allosteric regulation of Streptococcus mutans 2 '-deoxycytidylate deaminase
期刊论文
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2016, 卷号: 72, 期号: 7, 页码: 883-891
作者:
Dong YH(董宇辉)
;
Li YH(李艳华)
;
Gao ZQ(高增强)
;
Li, YH
;
Guo, Z
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2017/07/24
allosteric regulation
crystal structure
enzyme inactivation
enzyme mechanism
enzyme structure
2 '-deoxycytidylate deaminase
Streptococcus mutans
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