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大连化学物理研究所 [5]
昆明植物研究所 [2]
深圳先进技术研究院 [1]
湖南大学 [1]
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期刊论文 [8]
会议论文 [1]
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2019 [1]
2017 [1]
2016 [1]
2014 [1]
2013 [1]
2011 [2]
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Pharmacometabolomic prediction of individual differences of gastrointestinal toxicity complicating myelosuppression in rats induced by irinotecan.
期刊论文
Acta pharmaceutica Sinica. B, 2019, 卷号: No.1, 页码: 157-166
作者:
Yiqiao Gao
;
Wei Li
;
Jiaqing Chen
;
Xu Wang
;
Yingtong Lv
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/12/17
AUC-ROC,
area
under
receiver
operating
characteristic
BHB,
β-hydroxybutyric
acid
Biomarkers
C,
control
group
CA,
cholic
acid
CPT-11,
irinotecan
Complicating
toxicity
DBIL,
direct
bilirubin
DCA,
deoxycholic
acid
Diarrhea
FDR,
false
discovery
rate
GCA,
glycocholic
acid
Gastrointestinal
toxicity
IBIL,
indirect
bilirubin
IT-TOF/MS,
ion
trap/time-offlight
hybrid
mass
spectrometry
Individual
differences
Irinotecan
Lys,
lysine
MSTFA,
N-methyl-N-trifluoroacetamide
Metabolomics
NS,
non-sensitive
group
NSgt,
non-sensitive
for
gastrointestinal
toxicity
NSmt,
non-sensitive
for
myelosuppression
toxicity
OPLS-DA,
orthogonal
partial
least-squares-discriminant
analysis
PCA,
principal
component
analysis
PLS-DA,
partial
least-squares-discriminant
analysis
Phe,
phenylalanine
Prediction
QC,
quality
control
RSD,
relative
standard
deviation
S,
sensitive
group
Sgt,
sensitive
for
gastrointestinal
toxicity
Smt,
sensitive
for
myelosuppression
toxicity
T,
CPT-11
treated
group
Trp,
tryptophan
UFLC,
ultrafast
liquid
chromatography
VIP,
variable
importance
in
the
projection
pFDR,
false-discovery-rate-adjusted
P
value
UFLC-MS-IT-TOF and Bioassay Guided Isolation of Flavonoids as Xanthine Oxidase Inhibitors from Diospyros dumetorum
期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2017, 卷号: 12, 期号: 11, 页码: 1713-1715
作者:
Deng, Zhen-Tao
;
Yang, Tong-Hua
;
Huang, Xiao-Yan
;
Chen, Xing-Long
;
Zhang, Jian-Gang
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2018/05/08
Diospyros Dumetorum
Uflc-ms-it-tof
Bioassay-guided Isolation
Xod Inhibitory Activity
Flavonoids
Chemical profiles, antioxidant and anti-obesity effects of extract of Bambusa textilis McClure leaves
期刊论文
Journal of Functional Foods, 2016
作者:
Meng-Hua Liu
;
Chun-Hay Ko
;
Na Ma
;
Pei-Wen Tan
;
Wei-Ming Fu
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2017/01/13
UFLC/MS-IT-TOF guided isolation of anti-HBV active chlorogenic acid analogues from Artemisia capillaris as a traditional Chinese herb for the treatment of hepatitis
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2014, 卷号: 156, 期号: 10, 页码: 147-154
作者:
Zhao, Yong
;
Geng, Chang-An
;
Ma, Yun-Bao
;
Huang, Xiao-Yan
;
Chen, Hao
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2015/01/20
Artemisia capillaris
UFLC/MS-IT-TOF
Chlorogenic acid analogues
Anti-HBV activity
Serum lipid profiling of patients with chronic hepatitis B, cirrhosis, and hepatocellular carcinoma by ultra fast LC/IT-TOF MS
期刊论文
electrophoresis, 2013, 卷号: 34, 期号: 19, 页码: 2848-2856
作者:
Chen, Shili
;
Yin, Peiyuan
;
Zhao, Xinjie
;
Xing, Wenbin
;
Hu, Chunxiu
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2015/11/09
Lipidomics
LC-MS
Liver disease
Metabolomics
Phospholipids
Effect of the traditional Chinese medicine tongxinluo on endothelial dysfunction rats studied by using urinary metabonomics based on liquid chromatography-mass spectrometry
期刊论文
journal of pharmaceutical and biomedical analysis, 2011, 卷号: 56, 期号: 1, 页码: 86-92
作者:
Dai, Weidong
;
Wei, Cong
;
Kong, Hongwei
;
Jia, Zhenhua
;
Han, Jianke
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2012/07/09
Metabonomics
Urine
Endothelial dysfunction
LC-MS
Tongxinluo
Simvastatin
Serum lipid profiling of patients with chronic hepatitis B, cirrhosis and hepatocellular carcinoma by ultra fast liquid chromatography/ion trap-time of flight mass spectrometry
会议论文
37th international symposium on high performance liquid phase separations and related techniques, 大连, 2011-10-8
陈世礼
;
尹沛源
;
赵欣捷
;
WenbinXing
;
胡春秀
;
周丽娜
;
许国旺
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2012/07/09
Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry
期刊论文
molecular biosystems, 2010, 卷号: 6, 期号: 5, 页码: 852-861
作者:
Zhang, Fengxia
;
Jia, Zhenhua
;
Gao, Peng
;
Kong, Hongwei
;
Li, Xiang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2015/11/12
Metabonomics study of atherosclerosis rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry
期刊论文
talanta, 2009, 卷号: 79, 期号: 3, 页码: 836-844
作者:
Zhang, Fengxia
;
Jia, Zhenhua
;
Gao, Peng
;
Kong, Hongwei
;
Li, Xiang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2010/11/30
Atherosclerosis
Metabonomics
UFLC/MS-IT-TOF
Plasma
Urine
Rats
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