CORC

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CORC

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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia
收藏  |  浏览/下载：4/0  |  提交时间：2024/04/07
Targeting KRAS mutant cancers: from druggable therapy to drug resistance 期刊论文
MOLECULAR CANCER, 2022, 卷号: 21
作者:  Zhu, Chunxiao;  Guan, Xiaoqing;  Zhang, Xinuo;  Luan, Xin;  Song, Zhengbo
收藏  |  浏览/下载：23/0  |  提交时间：2022/12/23
Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRAS(G12C) inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 213, 页码: 17
作者:  Xiao, Xuanzheng;  Lai, Mengzhen;  Song, Zilan;  Geng, Meiyu;  Ding, Jian
收藏  |  浏览/下载：47/0  |  提交时间：2021/05/24
Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2020, 卷号: 19, 期号: 11, 页码: 2340-2352
作者:  Jin, Rui;  Liu, Liang;  Xing, Yun;  Meng, Tao;  Ma, Lanping
收藏  |  浏览/下载：50/0  |  提交时间：2020/12/24
EPHA2 feedback activation limits the response to PDE delta inhibition in KRAS-dependent cancer cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 270-277
作者:  Chen, Yue-hong;  Lv, Hao;  Shen, Ning;  Wang, Xiao-min;  Tang, Shuai
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01
Identification of a new inhibitor of KRAS-PDE delta interaction targeting KRAS mutant nonsmall cell lung cancer 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 5, 页码: 1334-1345
作者:  Leung, Elaine Lai-Han;  Luo, Lian Xiang;  Li, Ying;  Liu, Zhong-Qiu;  Li, Lan Lan
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Zoledronic acid enhances the efficacy of the MEK inhibitor trametinib in KRAS mutant cancers 期刊论文
Cancer Letters, 2019, 卷号: Vol.442, 页码: 202-212
作者:  Xinyu Dai;  Hongwei Xia;  Sheng Zhou;  Qiulin Tang;  Feng Bi
收藏  |  浏览/下载：8/0  |  提交时间：2019/02/28
A benzoxazole compound as a novel MEK inhibitor for the treatment of RAS/RAF mutant cancer 期刊论文
2019, 卷号: 145, 期号: 2, 页码: 586-596
作者:  Cheng, Ying;  Wang, Xingkai;  Xia, Xiangying;  Zhang, Wei;  Tian, Hongqi
收藏  |  浏览/下载：5/0  |  提交时间：2020/01/03
MiR-1205 functions as a tumor suppressor by disconnecting the synergy between KRAS and MDM4/E2F1 in non-small cell lung cancer 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2019, 卷号: 9, 期号: 2, 页码: 312-+
作者:  Yan, Hong;  Chen, Xiaoying;  Li, Yu;  Fan, Lei;  Tai, Yusi
收藏  |  浏览/下载：4/0  |  提交时间：2020/07/01
Deacetylmycoepoxydiene is an agonist of Rac1, and simultaneously induces autophagy and apoptosis 期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2018, 卷号: 102, 期号: 14, 页码: 5965-5975
作者:  Xie, Wei;  Zhang, Wei;  Sun, Mingwei;  Lu, Chunhua;  Shen, Yuemao
收藏  |  浏览/下载：35/0  |  提交时间：2018/12/21

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