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Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:
Gao, Dingding
;
Jin, Nan
;
Fu, Yixian
;
Zhu, Yueyue
;
Wang, Yujie
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/06/11
STAT3 signaling pathway
Benzothiazole
Rational design
Antitumor activity
Molecular docking
Cytotoxic phenolic constituents from Hypericum japonicum
期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 33-40
作者:
Zhu, Wei
;
Qiu, Jie
;
Zeng, Yan-Rong
;
Yi, Ping
;
Lou, Hua-Yong
收藏
  |  
浏览/下载:117/0
  |  
提交时间:2019/09/10
Hypericum japonicum thunb. (Hypericaceae)
Phenolic compounds
Xanthone and flavonoid derivatives
Cytotoxic activities
Structure-activity relationship
Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 8, 页码: 3898-3923
作者:
Liang, Xuewu
;
Zang, Jie
;
Li, Xiaoyang
;
Tang, Shuai
;
Huang, Min
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  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Design, synthesis, and cytotoxic activities of novel hybrids of parthenolide and thiazolidinedione via click chemistry
期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 页码: 9
作者:
Qiu, Jie
;
Yuan, Chun-Mao
;
Wen, Min
;
Li, Ya-Nan
;
Chen, Juan
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  |  
浏览/下载:44/0
  |  
提交时间:2019/07/29
Parthenolide-thiazolidinedione hybrids
click chemistry
cytotoxic activities
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:
Lin, Xin
;
Tian, Dongsong
;
Fu, Yanhui
;
Li, Yanan
;
Huang, Liejun
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  |  
浏览/下载:143/0
  |  
提交时间:2019/03/18
Polycyclic polyprenylated acylphloroglucinol
Chemical transformation
Cytotoxicity
Cell apoptosis
Cell cycle arrest
Combined inhibition of PI3K delta and FLT3 signaling exerts synergistic antitumor activity and overcomes acquired drug resistance in FLT3-activated acute myeloid leukemia
期刊论文
CANCER LETTERS, 2018, 卷号: 420, 页码: 49-59
作者:
He, Ye
;
Sun, Liping
;
Xu, Yongping
;
Fu, Li
;
Li, Yun
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  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Acute myeloid leukemia
FLT3
PI3K delta
CAL101
Synergistic effect
Isolation and Asymmetric Total Synthesis of Perforanoid A
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 卷号: 55, 期号: 26, 页码: 7539-7543
作者:
Lv, Chao
;
Yan, Xiaohui
;
Tu, Qian
;
Di, Yingtong
;
Yuan, Chunmao
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  |  
浏览/下载:24/0
  |  
提交时间:2016/11/04
asymmetric synthesis
cytotoxicity
limonoids
Pauson-Khand reaction
total synthesis
Total chemical synthesis of photoactivatable proteins for light-controlled manipulation of antigen-antibody interactions
期刊论文
CHEMICAL SCIENCE, 2016, 卷号: 7, 期号: 3, 页码: 1891-1895
作者:
Tang, Shan
;
Wan, Zhengpeng
;
Gao, Yiren
;
Zheng, Ji-Shen
;
Wang, Jing
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  |  
浏览/下载:15/0
  |  
提交时间:2017/11/06
Subcellular quantitative proteomic analysis reveals host proteins involved in human cytomegalovirus infection
期刊论文
Biochimica et biophysica acta-proteins and proteomics, 2015, 卷号: 1854, 期号: 8, 页码: 967-978
作者:
Chai, Fan
;
Li, Hao-Yu
;
Wang, Wei
;
Zhu, Xiu-Juan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/05/09
Human cytomegalovirus
Quantitative proteomics
Sirna
Few-layered graphene quantum dots as efficient hole-extraction layer for high-performance polymer solar cells
期刊论文
NANO ENERGY, 2015, 卷号: 15, 页码: 186-192
作者:
Ding, Zicheng
;
Hao, Zhen
;
Meng, Bin
;
Xie, Zhiyuan
;
Liu, Jun
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2015/12/21
Grapherie quantum dots
Grapherie oxide
Work function
Hole-extraction layer
Polymer solar cell
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