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上海药物研究所 [23]
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Bisphenol A (BPA) Directly Activates the G Protein-Coupled Estrogen Receptor 1 and Triggers the Metabolic Disruption in the Gonadal Tissue of Apostichopus japonicus
期刊论文
BIOLOGY-BASEL, 2023, 卷号: 12, 期号: 6, 页码: 19
作者:
Yuan, Jieyi
;
Yang, Jingwen
;
Xu, Xiuwen
;
Wang, Zexianghua
;
Jiang, Zhijing
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/01/26
Apostichopus japonicus
reproduction
estradiol receptor
Bisphenol A (BPA)
metabolic disruption
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 卷号: 404, 页码: 14
作者:
Wang, Ying
;
Zhu, Yao
;
Niu, Junxing
;
Deng, Qiangqiang
;
Guo, Shimeng
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  |  
浏览/下载:60/0
  |  
提交时间:2020/12/21
Bile acid analog
NASH
TGR5
Cd36
AMPK alpha
High-throughput screening campaign identifies a small molecule agonist of the relaxin family peptide receptor 4
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Lin, Guang-yao
;
Lin, Lin
;
Cai, Xiao-qing
;
Dai, An-tao
;
Zhu, Yue
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  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
RXFP4
INSL5
high-throughput screening
agonist
JK1
Sweroside promotes osteoblastic differentiation and mineralization via interaction of membrane estrogen receptor-alpha and GPR30 mediated p38 signalling pathway on MC3T3-E1 cells
期刊论文
PHYTOMEDICINE, 2020, 卷号: 68, 页码: 12
作者:
Wu, Qing-Chang
;
Tang, Xi-Yang
;
Dai, Zi-Qin
;
Dai, Yi
;
Xiao, Hui-Hui
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  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
Sweroside
Differentiation and mineralization
Membrane estrogen receptor-alpha
GPR30
P38 signaling pathway
MC3T3-E1 cells
Uncovering kappa-opioid receptor agonist-induced PAK1/2 phosphorylation by quantitative phosphoproteomics
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 516, 期号: 1, 页码: 320-326
作者:
Wu, Jianhong
;
Jiang, Qinghui
;
Zhu, Hongwen
;
Zhou, Yanting
;
Lu, Dayun
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  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
Dimethyl labeling
Kappa-opioid receptor
Kinase-substrate network
p21-activated kinases
Quantitative phosphoproteomics
Inhibition of MicroRNA-15a/16 Expression Alleviates Neuropathic Pain Development through Upregulation of G Protein-Coupled Receptor Kinase 2
期刊论文
BIOMOLECULES & THERAPEUTICS, 2019, 卷号: 27, 期号: 4
作者:
Li, Tao
;
Sun, Lijuan
;
Tao, Shoujun
;
Chen, Peng
;
Liu, Caihua
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  |  
浏览/下载:33/0
  |  
提交时间:2019/12/05
GRK2
miR-15a/16
Neuropathic pain
p38 MAPK
Mitogen-activated protein kinase signaling mediates opioid-induced presynaptic NMDA receptor activation and analgesic tolerance
期刊论文
JOURNAL OF NEUROCHEMISTRY, 2019, 卷号: 148, 期号: 2
作者:
Deng, Meichun
;
Chen, Shao-Rui
;
Chen, Hong
;
Luo, Yi
;
Dong, Yingchun
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  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
G protein-coupled receptor
NMDA receptor
opioid tolerance
primary afferent nerves
synaptic plasticity
mu-opioid receptor
Molecular characterization of G-protein-coupled receptor (GPCR) and protein kinase A (PKA) cDNA in Perinereis aibuhitensis and expression during benzo(a)pyrene exposure
期刊论文
PEERJ, 2019, 卷号: 7, 页码: e8044
作者:
Huang, Yi
;
Sun, Jia
;
Han, Ping
;
Zhao, Heling
;
Wang, Mengting
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2021/11/10
B(a)P
Perinereis aibuhitensis
GPCR
PKA
Real time PCR
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 24, 页码: 9370-9387
作者:
Lei, Saifei
;
Clydesdale, Lachlan
;
Dai, Antao
;
Cai, Xiaoqing
;
Feng, Yang
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
G protein-coupled receptor (GPCR)
glucagon
receptor structure-function
cell signaling
site-directed mutagenesis
biased agonism
GLP-1 receptor
glucagon-like peptide-1
class B peptide hormone
ERK kinase
arrestin
transmembrane domain
High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening
期刊论文
CHEMICAL SCIENCE, 2018, 卷号: 9, 期号: 12, 页码: 3192-3199
作者:
Qin, Shanshan
;
Meng, Mengmeng
;
Yang, Dehua
;
Bai, Wenwen
;
Lu, Yan
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  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
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