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浏览/检索结果:
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Anti-inflammatory activity of Anchusa italica Retz. in LPS-stimulated RAW264.7 cells mediated by the Nrf2/HO-1, MAPK and NF-κB signaling pathways
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 286, 期号: 3, 页码: 1-9
作者:
Duan, XM (Duan, Xiaomei) [1] , [2]
;
Li, J (Li, Jun) [1] , [2]
;
Cui, JX (Cui, Jingxue) [1] , [2]
;
Dong, YW (Dong, Yuwei) [1] , [2]
;
Xin, XL (Xin, Xuelei) [1] , [2]
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/05/17
Boraginaceae
Anchusa italica Retz.
Anti-inflammatory
Isolation and characterization of phellodendronoside A, a new isoquinoline alkaloid glycoside with anti-inflammatory activity from Phellodendron chinense Schneid
期刊论文
FITOTERAPIA, 2021, 卷号: 154
作者:
Si, Yanpo
;
Li, Xiaofei
;
Guo, Tao
;
Wei, Wenjun
;
Zhang, Jubao
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  |  
浏览/下载:25/0
  |  
提交时间:2021/12/17
Phellodendron chinense
Phellodendronoside A
Anti-inflammatory
MAPK pathway
Molecular docking
Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:
Wang, Yu-xiang
;
Zhang, Xu
;
Ma, Qing-yang
;
Hu, Lan-dian
;
Zhang, Xi
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  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
PD-L1 expression levels on tumor cells affect their immunosuppressive activity
期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 5, 页码: 5399-5407
作者:
Zheng, Yang
;
Fang, You-Chen
;
Li, Jing
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  |  
浏览/下载:53/0
  |  
提交时间:2020/07/01
programmed cell death 1
programmed death-ligand 1
co-culture
immunosuppression
signaling pathway
X-box binding protein l splicing attenuates brain microvascular endothelial cell damage induced by oxygen-glucose deprivation through the activation of phosphoinositide 3-kinase/protein kinase B, extracellular signal-regulated kinases, and hypoxia-inducible factor-1 alpha/vascular endothelial growth factor signaling pathways
期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: 234, 期号: 6
作者:
Shi, Shupeng
;
Tang, Mimi
;
Li, Honglei
;
Ding, Hui
;
Lu, Yangfan
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  |  
浏览/下载:41/0
  |  
提交时间:2019/12/04
angiogenesis
brain microvascular endothelial cells (BMECs)
ischemic stroke
X-box binding protein l splicing (XBP1s)
HMGB1 enhances mechanical stress-induced cardiomyocyte hypertrophy in vitro via the RAGE/ERK1/2 signaling pathway
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2019, 卷号: 44, 期号: 3
作者:
Zhang, Lei
;
Yang, Xue
;
Jiang, Guoliang
;
Yu, Ying
;
Wu, Han
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  |  
浏览/下载:29/0
  |  
提交时间:2019/12/05
cardiomyocyte hypertrophy
high mobility group box-1
mechanical stress
receptor for advanced glycation end products
extracellular signal-regulated kinase
Immunostimulatory Effects of Chitooligosaccharides on RAW 264.7 Mouse Macrophages via Regulation of the MAPK and PI3K/Akt Signaling Pathways
期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 1, 页码: 12
作者:
Yang, Yue
;
Xing, Ronge
;
Liu, Song
;
Qin, Yukun
;
Li, Kecheng
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  |  
浏览/下载:76/0
  |  
提交时间:2019/08/28
chitooligosaccharide
immunostimulatory activity
RAW 264
7 cells
mitogen-activated protein kinases (MAPK)
phosphoinositide 3-kinases (PI3K)
Akt
Role of the Extracellular Signal-Regulated Kinase 1/2 Signaling Pathway in Ischemia-Reperfusion Injury
期刊论文
FRONTIERS IN PHYSIOLOGY, 2019, 卷号: 10
作者:
Kong, Tingting
;
Liu, Minghui
;
Ji, Bingyuan
;
Bai, Bo
;
Cheng, Baohua
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/11
ERK1/2 signaling pathway
ischemia-reperfusion injury
protective
effect
damage effect
molecular mechanism
therapeutic target
Steroidal alkaloid solanine A from Solanum nigrum Linn. exhibits anti-inflammatory activity in lipopolysaccharide/interferon gamma-activated murine macrophages and animal models of inflammation
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 105, 期号: 2018, 页码: 606-615
作者:
Zhao, Lin
;
Wang, Lun
;
Di, Suo-ni
;
Xu, Qian
;
Ren, Qing-cuo
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/12/24
Solanine A
Solanum nigrum Linn.
Anti-inflammatory activity
NF-kappa B and MAPKs cascades
PI3K/Akt and JAK/STATs signalings
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 24, 页码: 9370-9387
作者:
Lei, Saifei
;
Clydesdale, Lachlan
;
Dai, Antao
;
Cai, Xiaoqing
;
Feng, Yang
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  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
G protein-coupled receptor (GPCR)
glucagon
receptor structure-function
cell signaling
site-directed mutagenesis
biased agonism
GLP-1 receptor
glucagon-like peptide-1
class B peptide hormone
ERK kinase
arrestin
transmembrane domain
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