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科研机构
西安交通大学 [2]
上海药物研究所 [2]
武汉物理与数学研究所 [2]
合肥物质科学研究院 [2]
兰州大学 [1]
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期刊论文 [12]
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Simulating androgen receptor selection in designer yeast
期刊论文
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2022, 卷号: 7
作者:
Zhang, Haoran
;
Zhang, Lu
;
Xu, Yipeng
;
Chen, Shaoyong
;
Ma, Zhenyi
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/23
Androgen receptor mutations
Androgen receptor antagonists
Prostate cancer
Saccharomyces cerevisiae
Enzalutamide-induced and PTH1R-mediated TGFBR2 degradation in osteoblasts confers resistance in prostate cancer bone metastases
期刊论文
CANCER LETTERS, 2022, 卷号: 525, 页码: 170-178
作者:
Su, Shang
;
Cao, Jingchen
;
Meng, Xiangqi
;
Liu, Ruihua
;
Vander Ark, Alexandra
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2022/01/04
Enzalutamide resistance
Prostate cancer
Bone microenvironment
TGFBR2
PTH1R
Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64
作者:
Fu, Weitao
;
Zhang, Minkui
;
Liao, Jianing
;
Tang, Qing
;
Lei, Yixuan
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/03/21
Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays
期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 16, 期号: 6, 页码: 416-427
作者:
Hou, Tingjun
;
Li, Dan
;
Chang, Shan
;
Xu, Lei
;
Sun, Huiyong
收藏
  |  
浏览/下载:260/0
  |  
提交时间:2019/06/24
Androgen receptor
AR ligand
Virtual screening
AR agonist
AR antagonist
Rational drug design for androgen receptor and glucocorticoids receptor dual antagonist
期刊论文
2019, 卷号: 166, 页码: 232-242
作者:
Wu, Meng
;
Xie, Yongli
;
Cui, Xiangling
;
Huang, Chenchao
;
Zhang, Rongyu
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  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
Prostate cancer
Enzalutamide resistance
Antagonist
Androgen receptor
Glucocorticoids receptor
Molecular Dynamics Simulations Revealed the Regulation of Ligands to the Interactions between Androgen Receptor and Its Coactivator
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2018, 卷号: 58, 期号: 8, 页码: 1652-1661
作者:
Liu, Na
;
Zhou, Wenfang
;
Guo, Yue
;
Wang, Junmei
;
Fu, Weitao
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2018/11/05
Natural killer cells suppress enzalutamide resistance and cell invasion in the castration resistant prostate cancer via targeting the androgen receptor splicing variant 7 (ARv7)
期刊论文
CANCER LETTERS, 2017, 卷号: 398, 页码: 62-69
作者:
Lin, Shin-Jen
;
Chou, Fu-Ju
;
Li, Lei
;
Lin, Chang-Yi
;
Yeh, Shuyuan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/26
Enzalutamide
Natural Killer cells
ARv7
Characterization of a novel p110 beta-specific inhibitor BL140 that overcomes MDV3100-resistance in castration-resistant prostate cancer cells
期刊论文
PROSTATE, 2017, 卷号: 77, 页码: 1187-1198
作者:
He, Chenchen
;
Duan, Shaofeng
;
Dong, Liang
;
Wang, Yifen
;
Hu, Qingting
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/11/26
p110beta
Enzalutamide
prostate cancer
PI3K
Characterization of a novel p110 beta-specific inhibitor BL140 that overcomes MDV3100-resistance in castration-resistant prostate cancer cells
期刊论文
PROSTATE, 2017, 卷号: 77, 期号: 11, 页码: 1187-1198
作者:
He Chenchen[1]
;
Duan Shaofeng[2]
;
Dong Liang[3]
;
Wang Yifen[4]
;
Hu Qingting[5]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/23
Enzalutamide
p110beta
PI3K
prostate cancer
Triptolide Inhibits the AR Signaling Pathway to Suppress the Proliferation of Enzalutamide Resistant Prostate Cancer Cells
期刊论文
THERANOSTICS, 2017, 卷号: 7, 期号: 7, 页码: 1914-1927
作者:
Han, Yangyang
;
Huang, Weiwei
;
Liu, Jiakuan
;
Liu, Dandan
;
Cui, Yangyan
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/01/08
Triptolide
Enzalutamide
Castration-resistant prostate cancer
Androgen receptor
Phosphorylation
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