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Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Wang, Zuo-wei
;
Zou, Feng-ming
;
Wang, Ao-li
;
Yang, Jing
;
Jin, Rui
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/22
AZD4547
RIPK1
inhibitors
SIRS model
anti-necroptosis
Genome and transcriptome-based characterization of high energy carbon-ion beam irradiation induced delayed flower senescence mutant in Lotus japonicus
期刊论文
BMC Plant Biology, 2021, 卷号: 21, 期号: 1, 页码: 19
作者:
Du,Yan
;
Luo,Shanwei
;
Zhao,Jian
;
Feng,Zhuo
;
Chen,Xia
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/12/08
Lotus japonicus
Flower senescence-delayed
Carbon-ion beam irradiation
Whole genome re-sequencing
RNA-seq
Phytohormone
Ionizing radiation downregulates estradiol synthesis via endoplasmic reticulum stress and inhibits the proliferation of estrogen receptor-positive breast cancer cells
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 11, 页码: 10
作者:
Yang, Pengfei
;
Feng, Xiu
;
Li, Jin
;
Zhang, Tianyi
;
Sheng, Chengyan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/12/13
PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery
期刊论文
AUTOPHAGY, 2021, 卷号: 17, 期号: 10, 页码: 2905-2922
作者:
Tang, Ying
;
Liu, Jinchang
;
Wang, Yu
;
Yang, Li
;
Han, Bing
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/01/04
Autophagy
functional recovery
ischemic stroke
lysophosphatidic acid receptor 5
microglial activation
poly (ADP-ribose) polymerase 14
Prevention of D-GalN/LPS-induced ALI by 18 beta-glycyrrhetinic acid through PXR-mediated inhibition of autophagy degradation
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 5, 页码: 13
作者:
Wu, Shouyan
;
Lu, Henglei
;
Wang, Wenjie
;
Song, Luyao
;
Liu, Meng
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/08/17
Engineering Nanoscale Artificial Antigen-Presenting Cells by Metabolic Dendritic Cell Labeling to Potentiate Cancer Immunotherapy
期刊论文
NANO LETTERS, 2021, 卷号: 21, 期号: 5, 页码: 2094-2103
作者:
Xiao, Ping
;
Wang, Jue
;
Zhao, Zitong
;
Liu, Xiaochen
;
Sun, Xiangshi
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
nanoscale
artificial antigen-presenting cells
metabolic cell labeling
dendritic cells
cancer immunotherapy
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
Combined cell death of co-exposure to aldehyde mixtures on human bronchial epithelial BEAS-2B cells: Molecular insights into the joint action
期刊论文
CHEMOSPHERE, 2020, 卷号: 244
作者:
Zhang, Sen
;
Zhang, Jingni
;
Cheng, Wanyan
;
Chen, Huan
;
Wang, An
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/11/26
Formaldehyde
Acrolein
Combined action
Cell death
Apoptotic signaling pathway
Tandem post-synthetic modification of a zeolitic imidazolate framework for CXCR4-overexpressed esophageal squamous cell cancer imaging and therapy
期刊论文
NANOSCALE, 2020, 卷号: 12, 期号: 24, 页码: 12779-12789
作者:
Cao, Yi
;
Jiang, Zhenqi
;
Li, Yanying
;
Wang, Yinjie
;
Yang, Yong
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/12/16
METAL-ORGANIC FRAMEWORKS
LYMPH-NODE METASTASIS
PREOPERATIVE CHEMORADIOTHERAPY
FAVORABLE BIOCOMPATIBILITY
CXCR4
EXPRESSION
AMPLIFICATION
PATTERNS
BINDING
TRAIL-based gene delivery and therapeutic strategies
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 11, 页码: 1373-1385
作者:
Zhong, Hui-hai
;
Wang, Hui-yuan
;
Li, Jian
;
Huang, Yong-zhuo
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2020/07/01
TRAIL
gene delivery
gene therapy
DNA
drug delivery systems
non-viral vectors
cancer therapy
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