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CORC

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Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
收藏  |  浏览/下载：21/0  |  提交时间：2020/12/21
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
收藏  |  浏览/下载：22/0  |  提交时间：2020/12/21
Structural optimization and neurotrophic activity evaluation of neurotrophic gentiside derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 22, 页码: 6
作者:  Wang, Zhenkang;  Ma, Chunhua;  Wang, Yujie;  Xiao, Qiang;  Xu, Chenghui
收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01
fDiscovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 72-85
作者:  Zhan, Wenhu;  Che, Jinxin;  Xu, Lei;  Wu, Yizhe;  Hu, Xiaobei
收藏  |  浏览/下载：15/0  |  提交时间：2020/07/01
Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-Based Design 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7264-7288
作者:  Dong, Xiaowu;  Zhan, Wenhu;  Zhao, Mengting;  Che, Jinxin;  Dai, Xiaoyang
收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01
Supramolecular Coordination-Directed Reversible Regulation of Protein Activities at Epigenetic DNA Marks 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 140, 期号: 46, 页码: 15842-15849
作者:  Xiong, Wei;  Wang, Shao-Ru;  Wang, Jia-Qi;  Fu, Bo-Shi;  Chen, Kun
收藏  |  浏览/下载：51/0  |  提交时间：2019/06/20
Supramolecular coordination-directed reversible regulation of protein activities at epigenetic dna marks 期刊论文
Journal of the american chemical society, 2018, 卷号: 140, 期号: 46, 页码: 15842-15849
作者:  Wang, Shao-Ru;  Wang, Jia-Qi;  Fu, Bo-Shi;  Chen, Kun;  Xiong, Wei
收藏  |  浏览/下载：48/0  |  提交时间：2019/05/08
Novel spirocyclic tranylcypromine derivatives as lysine-specific demethylase 1 (LSD1) inhibitors 期刊论文
RSC ADVANCES, 2018, 卷号: 8, 期号: 3, 页码: 1666-1676
作者:  Shi, Ying;  Wu, Yan-Ran;  Su, Ming-Bo;  Shen, Dong-Hao;  Gunosewoyo, Hendra
收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08
Stimulus-Responsive Plasmonic Chiral Signals of Gold Nanorods Organized on DNA Origami 期刊论文
NANO LETTERS, 2017, 卷号: 17, 期号: 11, 页码: 7125-7130
作者:  Jiang, Qiao;  Liu, Qing;  Shi, Yuefeng;  Wang, Zhen-Gang;  Zhan, Pengfei
收藏  |  浏览/下载：35/0  |  提交时间：2019/04/09
Zinc ion-induced conformational changes in new Delphi metallo-beta-lactamase 1 probed by molecular dynamics simulations and umbrella sampling 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 4, 页码: 3067-3075
作者:  Chen, Jianzhong;  Wang, Jinan;  Zhu, Weiliang
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08

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