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科研机构
中南大学 [36]
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期刊论文 [36]
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2018 [1]
2017 [2]
2016 [3]
2015 [4]
2014 [4]
2013 [7]
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专题:中南大学
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Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
Multidrug and toxin extrusion proteins mediate cellular transport of cadmium
期刊论文
Toxicology and Applied Pharmacology, 2017, 卷号: 314, 页码: 55-62
作者:
Yang, Hong
;
Guo, Dong
;
Obianom, Obinna N
;
Su, Tong
;
Polli, James E
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
Multidrug and toxin extrusion protein
Cadmium
Transporter
Toxicity
Detoxification
Kidney
Glutamate in peripheral organs: Biology and pharmacology
期刊论文
European Journal of Pharmacology, 2016, 卷号: 784, 页码: 42-48
作者:
Du, Jie
;
Li, Xiao-Hui
;
Li, Yuan-Jian*
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/03
Glutamic acid (PubChem CID:611)
Aspirin (PubChem CID:2244)
(RS)-1-aminoindan-1,5,dicarboxylic acid (AIDA) (PubChem CID:2071)
Dizocilpine (MK-801) (PubChem CID: 9862634)
2-amino-5-phosphono-valcrate (APV) (PubChem CID: 135342)
2-amino-7-phosphonoheptanoate (PubChem CID: 18538056)
6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) (PubChem CID: 3721046)
Phencyclidine (PCP) (PubChem CID: 6468)
Ketamine (PubChem CID: 3821)
Dextrorphan (PubChem CID: 5360697)
2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline (NBQX) (PubChem CID: 71312122)
Kynurenic acid (PubChem CID: 3845)
Quisqualate (PubChem CID: 40539)
Perampanel (PubChem CID: 9924495)
GYKI52466 (PubChem CID: 3538)
Gamma-aminomethyl sulfonate (PubChem CID: 2935)
LY367385 (PubChem CID: 5311261)
Glutamate
Glutamate receptor
Glutamate transporter
Peripheral tissues
N-methyl-D-aspartate receptor (NMDA receptor)
Different role of zinc transporter 8 between type 1 diabetes mellitus and type 2 diabetes mellitus
期刊论文
Journal of Diabetes Investigation, 2016, 卷号: 7, 期号: 4, 页码: 459-465
作者:
Yi, Bo
;
Huang, Gan
;
Zhou, Zhiguang*
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
Type 1 diabetes mellitus
Type 2 diabetes mellitus
Zinc transporter 8
A mutation in SLC22A4 encoding an organic cation transporter expressed in the cochlea strial endothelium causes human recessive non-syndromic hearing loss DFNB60
期刊论文
Human Genetics, 2016, 卷号: 135, 期号: 5, 页码: 513-524
作者:
Ben Said, Mariem
;
Grati, M'hamed
;
Ishimoto, Takahiro
;
Zou, Bing
;
Chakchouk, Imen
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
Hearing Loss
Hair Cell
Carnitine
Organic Cation Transporter
Apical Plasma Membrane
Beneficial effect of magnesium lithospermate B on cerebral ischemia-reperfusion injury in rats involves the regulation of miR-107/glutamate transporter 1 pathway
期刊论文
European Journal of Pharmacology, 2015, 卷号: 766, 页码: 91-98
作者:
Yang, Zhong-Bao
;
Luo, Xiu-Ju
;
Ren, Kai-Di
;
Peng, Jing-Jie
;
Tan, Bin
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/03
Brain
Glutamate transporter 1
Ischemia-reperfusion
Magnesium lithospermate B
miR-107
Glutamic acid decarboxylase autoantibodies are dominant but insufficient to identify most Chinese with adult-onset non-insulin requiring autoimmune diabetes: LADA China study 5
期刊论文
Acta Diabetologica, 2015, 卷号: 52, 期号: 6, 页码: 1121-1127
作者:
Xiang, Yufei
;
Huang, Gan
;
Shan, Zhongyan
;
Pan, Linlin
;
Luo, Shuoming
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/03
Glutamic acid decarboxylase antibody (GADA)
Insulin autoantibody (IAA)
Latent autoimmune diabetes of adults (LADA)
Protein tyrosine phosphatase-2 antibody (IA-2A)
Zinc transporter 8 autoantibody (ZnT8A)
Molecular imaging of striatal dopamine transporters in major depression - A meta-analysis
期刊论文
Journal of Affective Disorders, 2015, 卷号: 174, 页码: 137-143
作者:
Li, Zongchang
;
He, Ying
;
Tang, Jinsong
;
Zong, Xiaofen
;
Hu, Maolin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Depression
Dopamine transporter
Molecular imaging
Meta-analysis
Inhibition of soluble epoxide hydrolase in mice promotes reverse cholesterol transport and regression of atherosclerosis
期刊论文
Atherosclerosis, 2015, 卷号: 239, 期号: 2, 页码: 557-565
作者:
Shen, Li
;
Peng, Hongchun
;
Peng, Ran
;
Fan, Qingsong
;
Zhao, Shuiping
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
ATP binding cassette transporter A1
Epoxyeicosatrienoic acids
Soluble epoxide hydrolase
High density lipoprotein
Reverse cholesterol transport
ABCA1
ATP binding cassette transporter A1
HDL
high-density lipoprotein
RCT
reverse cholesterol transport
sEH
soluble epoxide hydrolase
EETs
epoxyeicosatrienoic acids
DHETs
dihydroxyeicosatrienoic acids
sEHI
sEH inhibitors
ATD
atherogenic diet
t-AUCB
trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid
SCD
standard chow diet
acLDL
acetylated LDL
LSC
liquid scintillation counting
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