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大连理工大学 [3]
上海生物化学与细胞生... [2]
上海药物研究所 [1]
中南大学 [1]
安徽大学 [1]
湖南大学 [1]
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期刊论文 [12]
发表日期
2018 [12]
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Direct fluorescence anisotropy approach for aflatoxin B1 detection and affinity binding study by using single tetramethylrhodamine labeled aptamer
期刊论文
TALANTA, 2018, 卷号: 189, 页码: 442-450
作者:
Sun, Linlin
;
Zhao, Qiang
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浏览/下载:220/0
  |  
提交时间:2019/06/20
Aptamer
Fluorescence anisotropy
Fluorescence polarization
Aflatoxin
Affinity ligand
Binding affinity
Recent Trends and Applications of Molecular Modeling in GPCR-Ligand Recognition and Structure-Based Drug Design
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 7
作者:
Yuan, Xiaojing
;
Xu, Yechun
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  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
GPCR
receptor-ligand recognition
drug design
molecular modeling
molecular dynamics
docking
binding affinity
binding pathway
Ligand Induced Folding of the First Identified CBM69 Starch Binding Domain AmyP-SBD
期刊论文
PROTEIN AND PEPTIDE LETTERS, 2018, 卷号: 25, 期号: 4, 页码: 362-367
作者:
Zhang, Wei
;
Yu, Jigang
;
Zhang, Xuecheng
;
Peng, Hui
;
Li, Xinxin
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  |  
浏览/下载:35/0
  |  
提交时间:2019/11/12
Starch binding domain
molten globule
ligand induced folding
carbohydrate binding module family 69
AmyP
nuclear magnetic resonance
Near-Infrared Light-Initiated Molecular Superoxide Radical Generator: Rejuvenating Photodynamic Therapy against Hypoxic Tumors
期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 140, 页码: 14851-14859
作者:
Li, Mingle
;
Xia, Jin
;
Tian, Ruisong
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  |  
浏览/下载:12/0
  |  
提交时间:2019/12/02
Cell death
Diseases
Infrared devices
Tumors, Cancer cell apoptosis
Hypoxic environments
Intravenous administration
Near infrared light
Personalized medicines
Photodynamic therapy (PDT)
Radical generation mechanisms
Therapeutic efficacy, Photodynamic therapy, antineoplastic agent
biotin
oxygen
superoxide, antihypoxia activity
apoptosis
Article
cancer cell
cancer inhibition
cancer tissue
cell transport
coculture
disease severity
dose response
drug activity
drug cytotoxicity
drug synthesis
human
in vitro study
in vivo study
ligand binding
neoplasm
nonhuman
patent
personalized medicine
photodynamic therapy
photoreactivity
radiation dose
rejuvenation
tumor ablation
tumor hypoxia
The Improved Delivery to Breast Cancer Based on a Novel Nanocarrier Modified with High-Affinity Peptides Discovered by Phage Display
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2018, 卷号: 7, 页码: e1800269
作者:
Zhang, Haoran
;
Guo, Zhaoming
;
He, Bing
;
Dai, Wenbing
;
Zhang, Hua
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/02
breast cancer
cell-binding peptides
cell-internalizing peptides
ligand-targeted nanosystems
phage display
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
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  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
In-situ liquid cell transmission electron microscopy investigation on oriented attachment of gold nanoparticles
期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9, 页码: 421
作者:
Zhu, Chao
;
Liang, Suxia
;
Song, Erhong
;
Zhou, Yuanjun
;
Wang, Wen
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/02
citric acid
gold nanoparticle
ligand, cell
chemical binding
crystal structure
gold
in situ measurement
ligand
liquid
nanoparticle
orientation
transmission electron microscopy, adsorption
Article
calculation
crystallization
energy
ligand binding
liquid
molecular dynamics
molecular stability
rotation
surface property
thickness
transmission electron microscopy
A comparative investigation of random and oriented immobilization of protein A ligands on the binding of immunoglobulin G
期刊论文
Biochemical Engineering Journal, 2018, 卷号: Vol.139, 页码: 15-24
作者:
Yang X.-H.
;
Huan L.-M.
;
Chu X.-S.
;
Sun Y.
;
Shi Q.-H.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/21
Adsorption capacity for IgG
Binding stoichiometry
Multimeric ligand
Oriented immobilization
Protein A chromatography
Ligand induced folding of the first identified CBM69 starch binding domain AmyP-SBD.
期刊论文
Protein And Peptide Letters, 2018
作者:
Zhang, W
;
Tu, XM
;
Li, XX
;
Peng, H
;
Zhang, JH
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/04/24
AmyP
Starch binding domain
carbohydrate binding module family 69
ligand induced folding
molten globule
nuclear magnetic resonance
Integrin alpha 4 beta 7 switches its ligand specificity via distinct conformer-specific activation
期刊论文
JOURNAL OF CELL BIOLOGY, 2018, 卷号: 217, 期号: 8, 页码: 2799-2812
作者:
Wang, ShiHui
;
Sun, Hao
;
Ge, GaoXiang
;
Chen, JianFeng
;
Wu, ChenYu
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/04/28
Selectin Glycoprotein Ligand-1
Cell-adhesion Molecule-1
Force Spectroscopy
P-selectin
Binding-sites
Structural Specializations
Neutrophil Adhesion
Chemokine Receptors
Crystal-structure
Domains
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