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浏览/检索结果: 共30条，第1-10条 帮助 限定条件 发表日期：2021    内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 17 作者:  Li, Xinzhi;  Yuan, Bingchuan;  Lu, Min;  Wang, Yuqin;  Ding, Na 收藏  |  浏览/下载：37/0  |  提交时间：2022/01/18 Exploring biological basis of Syndrome differentiation in coronary heart disease patients with two distinct Syndromes by integrated multi-omics and network pharmacology strategy 期刊论文 Chinese Medicine, 2021, 卷号: 16, 期号: 1 作者:  Wu,Gaosong;  Zhao,Jing;  Zhao,Jing;  Song,Nixue;  Zheng,Ningning 收藏  |  浏览/下载：24/0  |  提交时间：2021/12/01 Coronary heart disease  Syndrome differentiation  Traditional Chinese Medicine  Proteomics  Metabolomics  Network pharmacology   CsCCD2 Access Tunnel Design for a Broader Substrate Profile in Crocetin Production 期刊论文 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 39, 页码: 11626-11636 作者:  Liang, Nan;  Yao, Ming-Dong;  Wang, Ying;  Liu, Jia;  Feng, Lu 收藏  |  浏览/下载：20/0  |  提交时间：2021/12/01 crocetin  CCD2  access tunnel engineering  Saccharomyces cerevisiae   PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery 期刊论文 AUTOPHAGY, 2021, 卷号: 17, 期号: 10, 页码: 2905-2922 作者:  Tang, Ying;  Liu, Jinchang;  Wang, Yu;  Yang, Li;  Han, Bing 收藏  |  浏览/下载：45/0  |  提交时间：2022/01/04 Autophagy  functional recovery  ischemic stroke  lysophosphatidic acid receptor 5  microglial activation  poly (ADP-ribose) polymerase 14   Kynurenine derivative 3-HAA is an agonist ligand for transcription factor YY1 期刊论文 Journal of Hematology & Oncology, 2021, 卷号: 14, 期号: 1 作者:  Shi,Zhaopeng;  Gan,Guifang;  Xu,Xiang;  Zhang,Jieying;  Yuan,Yuan 收藏  |  浏览/下载：42/0  |  提交时间：2021/11/04 3-Hydroxyanthronic acid (3-HAA)  Kynurenine  YY1  DUSP6  Hepatocellular carcinoma (HCC)  Tryptophan metabolism   Novel selective kappa agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Wei, Yuan-yuan;  Ma, Yan;  Yao, Song-yu;  Kong, Ling-hui;  Liu, Xiao 收藏  |  浏览/下载：40/0  |  提交时间：2021/11/04 kappa-opioid receptor agonist  4,5-expoxymorphinan  antinociception  conditioned place aversion  sedation  U50,488H  morphine  Nor-BNI  beta-FNA   Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199 作者:  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Liang, Xiaoying;  Lan, Yuan 收藏  |  浏览/下载：43/0  |  提交时间：2021/11/04 Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Huang, He-ming;  Fan, Shi-jie;  Zhou, Xiao-ru;  Liu, Yan-jun;  Li, Xiao 收藏  |  浏览/下载：58/0  |  提交时间：2021/11/04 nonalcoholic steatohepatitis  inflammation  histone deacetylase inhibitor  givinostat  epigenetics   Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9458-9483 作者:  Huang, Huoming;  Li, Xueping;  Xie, Peng;  Li, Xinwei;  Xu, XueJun 收藏  |  浏览/下载：29/0  |  提交时间：2021/08/17 Four new diterpenoids from the twigs and leaves of Phyllanthus acidus 期刊论文 TETRAHEDRON, 2021, 卷号: 91, 页码: 6 作者:  Yuan, Yu-Rong;  Li, Yan-Wen;  Huang, Yi-Qi;  Liu, Qun-fang;  Ren, Yu-Hao 收藏  |  浏览/下载：34/0  |  提交时间：2021/08/17 Phyllanthus acidus  Cleistanthane-type diterpenoid  ECD calculation  Biosynthetic pathway  Cytotoxicity