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浏览/检索结果: 共12条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8 作者:  He, Zhi-di;  Zhang, Meng;  Wang, Yong-hui;  He, Yang;  Wang, Hai-rui 收藏  |  浏览/下载：33/0  |  提交时间：2021/05/24 tumor-targeted delivery  immunogenic cell death  PD-1  PD-L1 blockade  tumor immune microenvironment  irinotecan  JQ1  immune checkpoint   The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Yang, Fang-ming;  Fan, Di;  Yang, Xiao-qian;  Zhu, Feng-hua;  Shao, Mei-juan 收藏  |  浏览/下载：26/0  |  提交时间：2020/12/24 dry eye disease  artemisinin derivative  beta-aminoarteether maleate  inflammation  macrophages  TLR4  inflammasome   Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels 期刊论文 JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856 作者:  Liu, Wen;  Yin, Ye;  Wang, Meijing;  Fan, Ting;  Zhu, Yuyu 收藏  |  浏览/下载：237/0  |  提交时间：2020/12/24 Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)  hepatic steatosis  insulin resistance  caspase-1  interleukin 18 (IL-18)  fatty liver  metabolic disorder  inflammation  cytokine signaling  caspase 1 (CASP1)  tyrosine-protein phosphatase (tyrosine phosphatase)  macrophage   DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling 期刊论文 BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15 作者:  Li, Heng;  Li, Jian;  Zhang, Xianglei;  Feng, Chunlan;  Fan, Chen 收藏  |  浏览/下载：28/0  |  提交时间：2020/12/24 DC591017  PDE4  Inflammation  Macrophages  Dendritic cells  Psoriasis   DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling 期刊论文 BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15 作者:  Li, Heng;  Li, Jian;  Zhang, Xianglei;  Feng, Chunlan;  Fan, Chen 收藏  |  浏览/下载：40/0  |  提交时间：2020/12/24 DC591017  PDE4  Inflammation  Macrophages  Dendritic cells  Psoriasis   Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma 期刊论文 JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908 作者:  Dong, Liang-qing;  Peng, Li-hua;  Ma, Li-jie;  Liu, Dong-bing;  Zhang, Shu 收藏  |  浏览/下载：62/0  |  提交时间：2020/07/01 Hepatocellular carcinoma  Tumor heterogeneity  Tumor microenvironment  Immunoediting  Neoantigen   Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis 期刊论文 CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 4, 页码: 17 作者:  Li, Heng;  Feng, Chunlan;  Fan, Chen;  Yang, Yang;  Yang, Xiaoqian 收藏  |  浏览/下载：54/0  |  提交时间：2020/07/01 Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer's disease 期刊论文 ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 4, 页码: 646-666 作者:  Li, Xiaokang;  Lu, Jian;  Xu, Yixiang;  Wang, Jiaying;  Qiu, Xiaoxia 收藏  |  浏览/下载：45/0  |  提交时间：2020/07/01 Alzheimer's disease  Autophagy  Nitazoxanide  beta-amyloid  Tau protein   Supramolecular Prodrug Nanovectors for Active Tumor Targeting and Combination Immunotherapy of Colorectal Cancer 期刊论文 ADVANCED SCIENCE, 2020, 页码: 14 作者:  Hu, Xianli;  Hou, Bo;  Xu, Zhiai;  Saeed, Madiha;  Sun, Fang 收藏  |  浏览/下载：34/0  |  提交时间：2020/07/01 active tumor targeting  cancer management  colorectal cancer  combination immunotherapy  photodynamic immunotherapy  prodrugs  supramolecular nanovectors   Integrating yeast chemical genomics and mammalian cell pathway analysis (vol 40, pg 1245, 2020) 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 1 作者:  Zhou, Fu-lai;  Li, Sheena C.;  Zhu, Yue;  Guo, Wan-jing;  Shao, Li-jun 收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01