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CORC

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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia
收藏  |  浏览/下载：3/0  |  提交时间：2024/04/07
Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14
作者:  Zhang, Chun;  Sun, Yi-Tao;  Gao, Li-Xin;  Feng, Bo;  Yan, Xue
收藏  |  浏览/下载：16/0  |  提交时间：2022/01/18
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/01
Polyprenylated acylphloroglucinol meroterpenoids with PTP1B inhibition from Hypericum forrestii 期刊论文
FITOTERAPIA, 2021, 卷号: 153, 页码: 5
作者:  Zong, Jian-Fa;  Zhang, Meng-Meng;  Zhou, Yu-Bo;  Li, Jia;  Hou, Ai-Jun
收藏  |  浏览/下载：64/0  |  提交时间：2021/11/04
Synthesis and Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitory Activity Evaluation of Novel N-Acylhydrazone Derivatives Containing Carbazole and Aromatic Ring/Aromatic Fused Heterocycle 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 9, 页码: 3593-3607
作者:  Li Yingjun;  Lin Ledi;  Liu Jihong;  Gao Lixin;  Sheng Li
收藏  |  浏览/下载：18/0  |  提交时间：2021/12/01
Rearranged Diels-Alder Adducts and Prenylated Flavonoids as Potential PTP1B Inhibitors from Morus nigra 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 8, 页码: 2303-2311
作者:  Qu, Ke-Jun;  Wang, Bin;  Jiang, Chang-Sheng;  Xie, Bao-Gang;  Liu, Ai-Hong
收藏  |  浏览/下载：41/0  |  提交时间：2021/11/04
Synthesis of 5-Phenyl-1,3,4-thiadiazole Derivatives and Their Biochemical Evaluation against Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 (SHP1) 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3097-3105
作者:  Yu Lijie;  Feng Bo;  Wang Zhijia;  Gao Lixin;  Zhang Chun
收藏  |  浏览/下载：187/0  |  提交时间：2021/11/04
Synthesis and Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitory Activity Evaluation of Novel Arylaminoacetylhydrazone Derivatives Containing Carbazole Moiety 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3157-3170
作者:  Li Yingjun;  Lin Ledi;  Jin Kun;  Gao Lixin;  Sheng Li
收藏  |  浏览/下载：19/0  |  提交时间：2021/11/04
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei
收藏  |  浏览/下载：39/0  |  提交时间：2021/08/17
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
收藏  |  浏览/下载：31/0  |  提交时间：2021/05/11

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