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科研机构
上海药物研究所 [13]
内容类型
期刊论文 [13]
发表日期
2020 [13]
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浏览/检索结果:
共13条,第1-10条
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发表日期:2020
专题:上海药物研究所
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Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation
期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 13
作者:
Guo, An-Di
;
Wei, Dan
;
Nie, Hui-Jun
;
Hu, Hao
;
Peng, Chengyuan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/12/24
Supramolecular Assembly of TPE-Based Glycoclusters with Dicyanomethylene-4H-pyran (DM) Fluorescent Probes Improve Their Properties for Peroxynitrite Sensing and Cell Imaging
期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2020, 页码: 9
作者:
Dong, Lei
;
Fu, Mengqi
;
Liu, Lifang
;
Han, Hai-Hao
;
Zang, Yi
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/12/21
cell imaging
glycoclusters
peroxynitrite detection
self-assembly
tetraphenylethylene
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 卷号: 404, 页码: 14
作者:
Wang, Ying
;
Zhu, Yao
;
Niu, Junxing
;
Deng, Qiangqiang
;
Guo, Shimeng
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/12/21
Bile acid analog
NASH
TGR5
Cd36
AMPK alpha
Bioactive triterpenoids from Lantana camara showing anti-inflammatory activities in vitro and in vivo
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 10
作者:
Wu, Peng
;
Song, Ziteng
;
Wang, Xuelian
;
Li, Ying
;
Li, Yuhao
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2020/12/24
Euphane triterpenoids
Anti-inflammatory properties
Molecular docking
Zebrafish model
Lantana camara
Nitric oxide inhibitory iridoids as potential anti-inflammatory agents from Valeriana jatamansi
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9
作者:
Wang, Huimei
;
Song, Ziteng
;
Xing, Honghong
;
Shi, Zhaoyu
;
Wu, Peng
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/12/24
Iridoids
NO inhibitory activities
Valeriana jatamansi
Inflammation
Molecular docking
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
Liu, Wen
;
Yin, Ye
;
Wang, Meijing
;
Fan, Ting
;
Zhu, Yuyu
收藏
  |  
浏览/下载:237/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
Structural basis of GPBAR activation and bile acid recognition
期刊论文
NATURE, 2020, 页码: 29
作者:
Yang, Fan
;
Mao, Chunyou
;
Guo, Lulu
;
Lin, Jingyu
;
Ming, Qianqian
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/12/24
MT1-MMP-Activated Liposomes to Improve Tumor Blood Perfusion and Drug Delivery for Enhanced Pancreatic Cancer Therapy
期刊论文
ADVANCED SCIENCE, 2020, 页码: 14
作者:
Wei, Yan
;
Song, Sha
;
Duan, Nianxiu
;
Wang, Feng
;
Wang, Yuxi
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2020/12/24
membrane type 1-matrix metalloproteinase-activated cilengitide
pancreatic cancer
smart liposomes
vascular promotion
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 14
作者:
Xue, Ya-ru
;
Yao, Sheng
;
Liu, Qian
;
Peng, Zhao-liang
;
Deng, Qiang-qiang
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/07/01
gigantol
Chinese traditional medicine
liver injury
oxidative stress
inflammation
label-free proteomic
complement and coagulation cascades
terminal complement complex
Synthesis of triazolotriazine derivatives as c-Met inhibitors
期刊论文
MOLECULAR DIVERSITY, 2020, 页码: 8
作者:
Guo, Yuting
;
Peng, Xia
;
Ji, Yinchun
;
Zhang, Yitong
;
Ding, Jian
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/12/24
Receptor tyrosine kinase
c-Met
Triazolotriazine
SAR
Cellular potency
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