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科研机构
中南大学 [123]
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期刊论文 [123]
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2019 [1]
2018 [4]
2017 [16]
2016 [33]
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Circular RNA circMTO1 suppresses bladder cancer metastasis by sponging miR-221 and inhibiting epithelial-to-mesenchymal transition.
期刊论文
Biochemical and biophysical research communications, 2019, 卷号: 508, 期号: 4, 页码: 991-996
作者:
Li, Yixiao
;
Wan, Bo
;
Liu, Lei
;
Zhou, Lei*
;
Zeng, Qing*
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
*Biomarker
*Bladder cancer
*Circular RNA
*Epithelial-to-mesenchymal transition
*Metastasis
Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis
期刊论文
Redox Biology, 2018, 卷号: 16, 页码: 32-46
作者:
Han, Yachun
;
Xu, Xiaoxuan
;
Tang, Chengyuan
;
Gao, Peng
;
Chen, Xianghui
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/12/03
ALT
alanine aminotransferase
AST
aspartate aminotransferase
BUN
blood urea nitrogen
BW
body weight
BG
blood glucose
DCFDA
dichlorodihydrofluorescein diacetate
DN
diabetic nephropathy
ECL
enhanced chemiluminescence
EM
electron microscopy
EMT
epithelial–mesenchymal transition
HbA1C
hemoglobin A1c
HE
hematoxylin-eosin
IF
immunofluorescence
IHC
immunohistochemistry
KW
kidney weight
LDL
low-density lipoprotein
MDA
malondialdehyde
MFI
median fluorescence intensity
MMP
mitochondrial transmembrane potential
MMT
methyl methane-thiosulphonate
MPTP
mitochondrial permeability transition pore
MSU
monosodium urate
MtROS
mitochondria reactive oxygen species
PAS
periodic acid-Schiff
Scr
serum creatinine
TC
total cholesterol
TG
triglyceride
TBARS
thiobarbituric acid reactive substances
TPP
triphenylphosphonium
TRX
thioredoxin
TXNIP
thioredoxin-interacting protein
TUNEL
terminal deoxynucleotidyl transferase dUTP nick end-labeling
8-OHdG
8-oxo-deoxyguanosine
UA
uric acid
Diabetic nephropathy
Mitochondria
Reactive oxygen species (ROS)
TRX/TXNIP
NLRP3 inflammasome
MitoQ
Circulating Tumor Cells from Different Vascular Sites Exhibit Spatial Heterogeneity in Epithelial and Mesenchymal Composition and Distinct Clinical Significance in Hepatocellular Carcinoma
期刊论文
Clinical Cancer Research, 2018, 卷号: 24, 期号: 3, 页码: 547-559
作者:
Sun, Yun-Fan
;
Guo, Wei
;
Xu, Yang
;
Shi, Yin-Hong
;
Gong, Zi-Jun
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
Histone deacetylase inhibitors upregulate Snail via Smad2/3 phosphorylation and stabilization of Snail to promote metastasis of hepatoma cells
期刊论文
Cancer Letters, 2018, 卷号: 420, 页码: 1-13
作者:
Xu, Wei
;
Liu, Hao
;
Liu, Zhi-Gang
;
Wang, Hong-Sheng
;
Zhang, Fan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
Histone deacetylase inhibitors
Epithelial-mesenchymal transitions
Transcriptional activation
Snail stabilization
Tumor metastasis
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc
期刊论文
Redox Biology, 2017, 卷号: 13, 页码: 482-497
作者:
Yang, Shikun
;
Zhao, Li
;
Han, Yachun
;
Liu, Yu
;
Chen, Chao
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/03
DN
diabetic nephropathy
ROS
reactive oxygen species
HG
high-glucose
SIRT1
sirtuin-1
Ac-H3
acetyl-histone H3
STZ
streptozotocin
AMPK
AMP-activated protein kinase
ECM
extracellular matrix
Nox2
NADPH oxidase 2
EMT
tubular epithelial-mesenchymal transition
DAPI
4′,6-diamidino-2-phenylindole 9
DHE
dihydroethidium
NDRD
non-diabetic renal disease
H&E
hematoxylin-eosin
PAS
periodic acid-Schiff
PASM
periodic acid-silver methenamine
IHC
immunohistochemistry
MDA
malondialdehyde
ChIP
chromatin immunoprecipitation
TC
total cholesterol
BUN
blood urea nitrogen
FN
fibronectin
HBA1C
glycosylated hemoglobin
Scr
serum creatinine
TG
triglyceride
Probucol
Renal injury
Diabetic nephropathy
p66Shc
Autophagy inhibition impairs the epithelial-mesenchymal transition and enhances cisplatin sensitivity in nasopharyngeal carcinoma
期刊论文
Oncology letters, 2017, 卷号: 13, 期号: 6, 页码: 4147-4154
作者:
Su, Zhongwu
;
Li, Guo
;
Liu, Chao
;
Ren, Shuling
;
Deng, Tengbo
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/03
autophagy
chemoresistance
chloroquine
cisplatin
epithelial-mesenchymal transition
nasopharyngeal carcinoma
Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression
期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2017, 卷号: 50, 期号: 1, 页码: 252-262
作者:
Liu, Kaiyan
;
Tang, Zhenjie
;
Huang, Amin
;
Chen, Ping
;
Liu, Panpan
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
GAPDH
epithelial-mesenchymal transition
colon cancer
metastasis
glycolysis
SNAIL
The role of miRNA-223 in cancer: Function, diagnosis and therapy
期刊论文
Gene, 2017, 卷号: 616, 页码: 1-7
作者:
Gao, Yunliang
;
Lin, Le
;
Li, Tao
;
Yang, Jinrui*
;
Wei, Yongbao*
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/12/03
miRNAs
MicroRNAs
UTR
The 3′ untranslated region
oncomiRs
Oncogenic miRNAs
miR-223
miRNA-223
T-ALL
T-cell acute lymphoblastic leukemia
AML
Acute myeloid leukemia
NSCLC
Nonsmall cell lung cancer
C/EBP
CCAAT-enhancer-binding protein
NFI-A
Nuclear factor I-A
HSP90B1
Heat Shock Protein 90 kDa Beta Family Member 1
IGF-1R
Insulin-like growth factor-1 receptor
FOXO1
Transcription factor Forkhead box O1
NPC
Nasopharyngeal carcinoma
EMT
Epithelial-to-mesenchymal transformation
Mef2c
Myocyte enhancer factor 2c
EBV
Epstein–Barr virus
JMML
Juvenile myelomonocytic leukemia
EPB41L3
Erythrocyte membrane protein band 4.1-like 3
HCC
Hepatocellular carcinoma
miR-223
Cancer
Biological function
Oncogene
Tumor promoter
Biomarker
Oncotherapy
miR-302b inhibits tumorigenesis by targeting EphA2 via Wnt/ β-catenin/EMT signaling cascade in gastric cancer
期刊论文
BMC Cancer, 2017, 卷号: 17, 期号: 1, 页码: 886
作者:
Huang, Jin
;
He, Yijing
;
Mcleod, Howard L
;
Xie, Yanchun
;
Xiao, Desheng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
*EphA2
*Epithelial-mesenchymal transition
*Gastric cancer
*Wnt/beta-catenin
*miR-302b
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