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科研机构
上海药物研究所 [69]
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期刊论文 [67]
会议论文 [1]
学位论文 [1]
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2021 [4]
2020 [7]
2019 [6]
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PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery
期刊论文
AUTOPHAGY, 2021, 卷号: 17, 期号: 10, 页码: 2905-2922
作者:
Tang, Ying
;
Liu, Jinchang
;
Wang, Yu
;
Yang, Li
;
Han, Bing
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/01/04
Autophagy
functional recovery
ischemic stroke
lysophosphatidic acid receptor 5
microglial activation
poly (ADP-ribose) polymerase 14
Identification of novel anti-inflammatory Nur77 modulators by virtual screening
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 7
作者:
Ding, Xiaoyu
;
Zhao, Zijie
;
Wu, Yue
;
Zhang, Hao
;
Chen, Kaixian
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/08/17
Nur77
Binding site evaluation
Virtual Screening
Inflammation
Prevention of D-GalN/LPS-induced ALI by 18 beta-glycyrrhetinic acid through PXR-mediated inhibition of autophagy degradation
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 5, 页码: 13
作者:
Wu, Shouyan
;
Lu, Henglei
;
Wang, Wenjie
;
Song, Luyao
;
Liu, Meng
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/08/17
Engineering Nanoscale Artificial Antigen-Presenting Cells by Metabolic Dendritic Cell Labeling to Potentiate Cancer Immunotherapy
期刊论文
NANO LETTERS, 2021, 卷号: 21, 期号: 5, 页码: 2094-2103
作者:
Xiao, Ping
;
Wang, Jue
;
Zhao, Zitong
;
Liu, Xiaochen
;
Sun, Xiangshi
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/05/24
nanoscale
artificial antigen-presenting cells
metabolic cell labeling
dendritic cells
cancer immunotherapy
Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15153-15186
作者:
Zheng, Wei
;
Wang, Zhen
;
Jiang, Xiangrui
;
Zhao, Qingjie
;
Shen, Jingshan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
Ternary Regulation of Tumor Microenvironment by Heparanase-Sensitive Micelle-Loaded Monocytes Improves Chemo-Immunotherapy of Metastatic Breast Cancer
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 12
作者:
Lang, Tianqun
;
Zheng, Zhong
;
Huang, Xin
;
Liu, Yiran
;
Zhai, Yihui
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/05/24
breast cancer
chemo-immunotherapy
heparinase
monocytes
tumor environments
Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298
作者:
Ding, Chunyong
;
Song, Zilan
;
Shen, Ancheng
;
Chen, Tingting
;
Zhang, Ao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Immunotherapy
Anti-tumor
cGAS
STING
TBK1
Small molecule modulators
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
The triterpenoid sapogenin (2 alpha-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling
期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 9, 页码: 10
作者:
Xie, Zhifu
;
Jiang, Haowen
;
Liu, Wei
;
Zhang, Xinwen
;
Chen, Dakai
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/12/21
Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Gao, Jing
;
Wang, Wei-qi
;
Pei, Qing
;
Lord, Megan S.
;
Yu, Hai-jun
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
cancer immunotherapy
immunogenic cell death
immunosuppressive tumor microenvironment
nanomedicine
drug delivery systems
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