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浏览/检索结果: 共5条，第1-5条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文 BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13 作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun 收藏  |  浏览/下载：31/0  |  提交时间：2021/12/01 2,5-diphenyl-1,3,4-oxadiazole derivatives  SHP2  Inhibitors  Structure-activity relationships (SAR)   Allosteric Inhibitors of SHP2: An Updated Patent Review (2015-2020) 期刊论文 CURRENT MEDICINAL CHEMISTRY, 2021, 卷号: 28, 期号: 19, 页码: 3825-3842 作者:  Wu, Jingwei;  Zhang, Huan;  Zhao, Guilong;  Wang, Runling 收藏  |  浏览/下载：65/0  |  提交时间：2021/08/17 SHP2 inhibitor  PTPN11 gene  allosteric  cancer  combination therapy  clinical trial   Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5 作者:  Satheeshkumar, Rajendran;  Zhu, Rui;  Feng, Bo;  Huang, Chao;  Gao, Ya 收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01 Heterocyclic bis-aryl amides  PTP1B  SHP2  Inhibitors  Structure-activity relationships (SAR)   Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 3, 页码: 778-781 作者:  Zhang, Li;  Jiang, Cheng-Shi;  Gao, Li-Xin;  Gong, Jing-Xu;  Wang, Zhong-Hua 收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 Phidianidine  Oxadiazole derivative  PTP1B inhibitor  Specific selectivity  Docking analysis  Function-oriented synthesis   Establishment and Application of High -throughput Screening Model for SHP2 Inhibitors 期刊论文 Science & Technology Review, 2014, 卷号: 32, 期号: 4-5, 页码: 91-94 作者:  Gao Wei;  Shao Wei;  Su Gang;  Li Jia;  Xie Xiaodong 收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 SHP2  SHP2  inhibitor  high throughput screening