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科研机构
上海药物研究所 [67]
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期刊论文 [66]
项目 [1]
发表日期
2021 [2]
2020 [6]
2019 [3]
2018 [6]
2017 [8]
2016 [3]
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Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2021, 卷号: 17, 期号: 9, 页码: 19
作者:
Xiong, Zhaoping
;
Jeon, Minji
;
Allaway, Robert J.
;
Kang, Jaewoo
;
Park, Donghyeon
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/11/04
Bio-inspired amyloid polypeptides: From self-assembly to nanostructure design and biotechnological applications
期刊论文
APPLIED MATERIALS TODAY, 2021, 卷号: 22, 页码: 23
作者:
Lai, Yi
;
Li, Fenglin
;
Zou, Zhifeng
;
Saeed, Madiha
;
Xu, Zhiai
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/05/24
Amyloid polypeptide
Bio-inspired
Nanomedicine
Self-assembly
Dependence of PINK1 accumulation on mitochondrial redox system
期刊论文
AGING CELL, 2020, 页码: 14
作者:
Gao, Feng
;
Zhang, Yan
;
Hou, Xiaoou
;
Tao, Zhouteng
;
Ren, Haigang
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/12/24
autophagy
mitochondrion
mitophagy
neurodegenerative diseases
PINK1
Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5
期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 12, 页码: 18
作者:
Han, Haozhen
;
Li, Chunpu
;
Li, Man
;
Yang, Lisheng
;
Zhao, Sen
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/12/24
sirtuins
inhibitor
structure-activity relationship
deacetylase
Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 4, 页码: 483-498
作者:
Xu, Ming-ming
;
Ryan, Philip
;
Rudrawar, Santosh
;
Quinn, Ronald J.
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
Recent advances in dopaminergic strategies for the treatment of Parkinson's disease
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Mao, Qi
;
Qin, Wang-zhi
;
Zhang, Ao
;
Ye, Na
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Parkinson's disease
dopamine
D-1 receptor
D-2 receptor
allosteric modulator
neuroprotection
multitarget
drug discovery and development
neurodegenerative diseases
advancesinthedevelopmentofimagingprobesandaggregationinhibitorsforalphasynuclein
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 4, 页码: 483
作者:
Xu Mingming
;
Ryan Philip
;
Rudrawar Santosh
;
Quinn Ronald J
;
Zhang Haiyan
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Parkinson’s disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
recentadvancesindopaminergicstrategiesforthetreatmentofparkinsonsdisease
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 4, 页码: 471
作者:
Mao Qi
;
Qin Wangzhi
;
Zhang Ao
;
Ye Na
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Parkinson’s disease
dopamine
D_1 receptor
D_2 receptor
allosteric modulator
neuroprotection
multitarget
drug discovery and development
neurodegenerative diseases
Neuroprotective Effect of Natural Alkaloid Fangchinoline Against Oxidative Glutamate Toxicity: Involvement of Keap1-Nrf2 Axis Regulation
期刊论文
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2019, 卷号: 39, 期号: 8, 页码: 1177-1186
作者:
Bao, Fengxia
;
Tao, Lingxue
;
Zhang, Haiyan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Fangchinoline
Keap1
Nrf2
Oxidative stress
Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 16, 页码: 20
作者:
Huang, Xing
;
Li, Ning
;
Pu, Yiqiong
;
Zhang, Tong
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
neuroprotective effects
ginseng
Alzheimer's disease
ginsenoside
Parkinson's disease
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