Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives

doi:10.3390/molecules24162939

	Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives
	Huang, Xing 2,3; Li, Ning 1,4; Pu, Yiqiong 3; Zhang, Tong 2,3; Wang, Bing 2,5
刊名	MOLECULES
	2019-08-01
卷号	24 期号:16 页码:20
关键词	neuroprotective effects ginseng Alzheimer's disease ginsenoside Parkinson's disease
DOI	10.3390/molecules24162939
通讯作者	Zhang, Tong(zhangtdmj@hotmail.com) ; Wang, Bing(bwang@simm.ac.cn)
英文摘要	As our global population ages, the treatment of neurodegenerative diseases is critical to our society. In recent years, researchers have begun to study the role of biologically active chemicals from plants and herbs to gain new inspiration and develop new therapeutic drugs. Ginseng (Panax ginseng C.A. Mey.) is a famous Chinese herbal medicine with a variety of pharmacological activities. It has been used to treat various diseases since ancient times. Extensive research over the years has shown that ginseng has potential as a neuroprotective drug, and its neuroprotective effects can be used to treat and prevent neurological damage or pathologically related diseases (such as Alzheimer's disease, Parkinson's disease, Huntington's disease, depression symptoms, and strokes). Moreover, evidence for the medicinal and health benefits of ginsenoside, its main active ingredient, in the prevention of neurodegenerative diseases is increasing, and current clinical results have not reported any serious adverse reactions to ginseng. Therefore, we briefly review the recent research and development on the beneficial effects and mechanisms of ginseng and its main active ingredient, ginsenoside, in the prevention and treatment of neurodegenerative diseases, hoping to provide some ideas for the discovery and identification of ginseng neuroprotection.
资助项目	Program of Shanghai Committee of Science and Technology, China[17401902300] ; Program of Shanghai Academic/Technology Research Leader, China[18XD1403700] ; Applied Basic Research Programs of Yunnan Province, China[2018FB141]
WOS关键词	ACUTE ISCHEMIC-STROKE ; OXYGEN-GLUCOSE DEPRIVATION ; CEREBRAL-ISCHEMIA ; PANAX-GINSENG ; PARKINSONS-DISEASE ; OXIDATIVE STRESS ; NEURONAL DEGENERATION ; REPERFUSION INJURY ; RB1S ATTENUATION ; ALPHA-SYNUCLEIN
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
出版者	MDPI
WOS记录号	WOS:000482998900072
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/288757]
专题	中国科学院上海药物研究所
通讯作者	Zhang, Tong; Wang, Bing
作者单位	1.KPC Pharmaceut Inc, Res Inst, Kunming 650106, Yunnan, Peoples R China 2.Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai 201203, Peoples R China 3.Shanghai Univ Tradit Chinese Med, Expt Ctr Teaching & Learning, Shanghai 201203, Peoples R China 4.Shanghai Univ Tradit Chinese Med, Inst Chinese Mat Med, Shanghai 201203, Peoples R China 5.Chinese Acad Sci, Shanghai Inst Mat Med, Pharmaceut Res Ctr, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Huang, Xing,Li, Ning,Pu, Yiqiong,et al. Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives[J]. MOLECULES,2019,24(16):20.
APA	Huang, Xing,Li, Ning,Pu, Yiqiong,Zhang, Tong,&Wang, Bing.(2019).Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives.MOLECULES,24(16),20.
MLA	Huang, Xing,et al."Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives".MOLECULES 24.16(2019):20.