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科研机构
上海药物研究所 [54]
内容类型
期刊论文 [54]
发表日期
2021 [8]
2020 [3]
2019 [8]
2018 [2]
2017 [1]
2016 [6]
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Huangjinsan ameliorates adenine-induced chronic kidney disease by regulating metabolic profiling
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 11
作者:
Guo, Yuejiao
;
Liu, Fang
;
Chen, MingCang
;
Tian, Qiang
;
Tian, Xiaoting
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/16
chronic kidney disease
Huangjinsan
metabolomics
renoprotection
traditional Chinese medicine
Restoring perturbed oxylipins with Danqi Tongmai Tablet attenuates acute myocardial infarction
期刊论文
PHYTOMEDICINE, 2021, 卷号: 90, 页码: 12
作者:
Zhi, Haijuan
;
Zhang, Zijia
;
Deng, Yanping
;
Yan, Bingpeng
;
Li, Zhenwei
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/11/04
Acute myocardial infarction
Danqi Tongmai tablet
In vivo metabolite
Oxylipin
Arachidonic acid metabolome
Homeostasis
Absorption, distribution, metabolism, and excretion of [C-14]NBP (3-n-butylphthalide) in rats
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 9
作者:
Tian, Junjun
;
Lei, Peng
;
He, Yifei
;
Zhang, Ning
;
Ge, Xinyu
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/11/04
3-n-butylphthalide (NBP)
[C-14]NBP
Pharmacokinetics
Tissue distribution
Metabolism
Mass balance
Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273
作者:
Chen, Zhen-dong
;
Chen, Qian
;
Zhu, Yun-ting
;
Zhang, Yi-fan
;
Zhan, Yan
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/01/04
henagliflozin
food effects
mass balance
pharmacokinetics
SGLT-2 inhibitor
Qualitatively and quantitatively investigating the metabolism of 20(S)-protopanaxadiol-type ginsenosides by gut microbiota of different species
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2021, 页码: 8
作者:
Zhang, Ying
;
Yao, Lingling
;
Tang, Chunping
;
Jiang, Jianlan
;
Ye, Yang
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/11/04
gut microbiota
LC-MS
PPD-type ginsenosides
species
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439
期刊论文
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893
作者:
Shackleford, David M.
;
Chiu, Francis C. K.
;
Katneni, Kasiram
;
Blundell, Scott
;
McLaren, Jenna
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/11/04
OZ439 (artefenomel)
malaria
metabolite identification
cytochrome P450 metabolism
cytochrome P450 inhibition
time-dependent inhibition
Characterization and quantitative determination of henagliflozin metabolites in humans
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 192, 页码: 8
作者:
Chen, Zhendong
;
Li, Liang
;
Zhan, Yan
;
Zhang, Yifan
;
Liu, Haiyan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
Henagliflozin
Metabolism
LC-MS/MS
Pyrrolidinyl Synthetic Cathinones alpha-PHP and 4F-alpha-PVP Metabolite Profiling Using Human Hepatocyte Incubations
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 1, 页码: 17
作者:
Carlier, Jeremy
;
Diao, Xingxing
;
Giorgetti, Raffaele
;
Busardo, Francesco P.
;
Huestis, Marilyn A.
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/05/24
alpha-PHP
PV7
4F-alpha-PVP
novel psychoactive substance
synthetic cathinone
bath salt
hepatocyte metabolism
liquid chromatography-high resolution tandem mass spectrometry
Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway
期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 13
作者:
Xue, Yaru
;
Deng, Qiangqiang
;
Zhang, Qingli
;
Ma, Zhenghua
;
Chen, Binfan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Systematic investigation on the chemical basis of anti-NAFLD Qushi Huayu Fang. Part 1: A study of metabolic profiles in vivo and in vitro by high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 15
作者:
Liu, Huan
;
Sun, Zhaolin
;
Tian, Xiaoting
;
Feng, Qin
;
Guo, Ziqiong
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
HPLC-Q-TOF
intestinal bacteria
liver
metabolism
Qushi Huayu Fang
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