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上海药物研究所 [9]
复旦大学上海医学院 [2]
中国医学科学院 北京... [2]
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四川大学 [1]
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期刊论文 [17]
会议论文 [1]
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Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Absorption, distribution, metabolism, and excretion of [C-14]NBP (3-n-butylphthalide) in rats
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 9
作者:
Tian, Junjun
;
Lei, Peng
;
He, Yifei
;
Zhang, Ning
;
Ge, Xinyu
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/11/04
3-n-butylphthalide (NBP)
[C-14]NBP
Pharmacokinetics
Tissue distribution
Metabolism
Mass balance
New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites
期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 15
作者:
Diao, Xingxing
;
Huestis, Marilyn A.
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
novel psychoactive substances
NPS
synthetic cannabinoid
SC
metabolism
urinary metabolites
hepatocyte incubation
dl-3n-butylphthalide reduces oxygen-glucose deprivation-induced endothelial cell damage by increasing PGC-1 alpha
期刊论文
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2019, 卷号: 23, 期号: 10
作者:
Wei, H.
;
Zhan, L-P
;
Zhang, B.
;
Li, Y-P
;
Pei, Z.
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/04
NBP
Endothelial injury
Hypoxia
eNOS
PGC-1 alpha
Dl-3-n-Butylphthalide Inhibits NLRP3 Inflammasome and Mitigates Alzheimer's-Like Pathology via Nrf2-TXNIP-TrX Axis
期刊论文
Antioxidants & Redox Signaling, 2019, 卷号: Vol.30 No.11, 页码: 1411-1431
作者:
Chun-Yan Wang
;
Ye Xu
;
Xu Wang
;
Chuang Guo
;
Tao Wang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/13
Alzheimer's disease
APP/PS1 transgenic mouse
Nrf2-TXNIP-TrX axis
Dl-NBP
NLRP3 inflammasome
Dl-3-n-Butylphthalide (NBP): A Promising Therapeutic Agent for Ischemic Stroke
期刊论文
2018, 卷号: 17, 期号: 5, 页码: 338-347
作者:
Wang, Shan
;
Ma, Fei
;
Huang, Longjian
;
Zhang, Yong
;
Peng, Yuchen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Dl-3-n-butylphthalide
ischemic stroke
cerebral microcirculation
neuroprotection
mitochondria
apoptosis
oxidative stress
Conversion and pharmacokinetics profiles of a novel pro-drug of 3-n-butylphthalide, potassium 2-(1-hydroxypentyl)-benzoate, in rats and dogs
期刊论文
2018, 卷号: 39, 期号: 2, 页码: 275-285
作者:
Li, Jiang
;
Xu, Shao-feng
;
Peng, Ying
;
Feng, Nan
;
Wang, Ling
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/01/03
potassium 2-(1-hydroxypentyl)-benzoate (dl-PHPB)
pro-drug
3-n-butylphthalide (dl-NBP)
ischemic stroke
pharmacokinetics
bioavailability
Effects of Dl-3-n-butylphthalide on Cerebral Ischemia Infarction in Rat Model by Mass Spectrometry Imaging
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 卷号: 18, 期号: 11
作者:
Liu, Run-Zhe
;
Fan, Chao-Xin
;
Zhang, Zhi-Lin
;
Zhao, Xin
;
Sun, Yi
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/04/09
Dl-3-n-butylphthalide
Permanent Middle Cerebral Artery Occlusion (Pmcao)
Matrix-assisted Laser Desorption Time Of Flight Ionization Mass Spectrometry Imaging (maldi-tOf-ms Imaging)
Metabolites
DL-3-n-butylphthalide-Edaravone hybrids as novel dual inhibitors of amyloid-β aggregation and monoamine oxidases with high antioxidant potency for Alzheimer\'s therapy.
期刊论文
Bioorganic & Medicinal Chemistry Letters, 2017, 卷号: Vol.27 No.4, 页码: 718-722
作者:
Qiang X
;
Li Y
;
Yang X
;
Luo L
;
Xu R
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/02/25
Alzheimer’s disease
Antioxidant
Aβ aggregation inhibitors
DL-NBP-Edaravone hybrids
MAO inhibitors
Effects of dI-3-n-butylphthalide on serum VEGF and bFGF levels in acute cerebral infarction
期刊论文
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2017, 卷号: 21, 期号: 19, 页码: 4431-4436
作者:
Tang, S. -C.
;
Luo, C. -J.
;
Zhang, K. -H.
;
Li, K.
;
Fan, X. -H.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Acute cerebral infarction
Vascular endothelial growth factor
Basic
fibroblast growth factor
NBP
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