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科研机构
上海药物研究所 [37]
内容类型
期刊论文 [37]
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2020 [2]
2019 [4]
2018 [5]
2017 [3]
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DCZ3301, an aryl-guanidino agent, inhibits ocular neovascularization via PI3K/AKT and ERK1/2 signaling pathways
期刊论文
EXPERIMENTAL EYE RESEARCH, 2020, 卷号: 201, 页码: 8
作者:
Xu, Kai
;
Li, Bo
;
Zhang, Shujie
;
Hu, Fangyuan
;
Xu, Zhijian
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
DCZ3301
Apoptosis
PI3K/AKT pathway
ERK1/2 pathway
Choroid microvascular sprouting
Corneal neovascularization
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 13
作者:
Yuliantie, Elita
;
Darbalaei, Sanaz
;
Dai, Antao
;
Zhao, Peishen
;
Yang, Dehua
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
G protein-coupled receptor
Glucose-dependent insulinotropic peptide receptor
Glucagon-like peptide-1 receptor
Biased agonist
GPCR signaling
Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas
期刊论文
BMC CANCER, 2019, 卷号: 19, 期号: 1, 页码: 13
作者:
Zhang, Qing
;
Liu, Jian-He
;
Liu, Jing-Li
;
Qi, Chun-Ting
;
Yan, Lei
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2020/07/01
Receptor tyrosine kinases (RTKs)
Activation and function
Clear cell renal cell carcinomas (ccRCCs)
Targeted therapy
PDGFR beta
Stroma cells
SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met
期刊论文
CANCER SCIENCE, 2019, 页码: 11
作者:
Tong, Mengya
;
Gao, Mingzhao
;
Xu, Yongping
;
Fu, Li
;
Li, Yun
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
AZD9291
c-Met ADC
c-Met overexpression
resistance
SHR-A1403
Inhibition of MAPK/ERK pathway promotes oligodendrocytes generation and recovery of demyelinating diseases
期刊论文
GLIA, 2019, 卷号: 67, 期号: 7, 页码: 1320-1332
作者:
Suo, Na
;
Guo, Yu-e
;
He, Bingqing
;
Gu, Haifeng
;
Xie, Xin
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
differentiation
ERK
MAPK
MEK inhibitor
myelin
oligodendrocyte
oligodendrocyte progenitor cell
remyelination
DCZ0801, a novel compound, induces cell apoptosis and cell cycle arrest via MAPK pathway in multiple myeloma
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2019, 卷号: 51, 期号: 5, 页码: 517-523
作者:
Zhang, Ting
;
Li, Bo
;
Feng, Qilin
;
Xu, Zhijian
;
Huang, Cheng
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
DCZ0801
multiple myeloma
apoptosis
cell cycle
MAPK
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors
期刊论文
CELL, 2018, 卷号: 175, 期号: 1, 页码: 186-+
作者:
Huang, Xun
;
Yan, Juan
;
Zhang, Min
;
Wang, Yafang
;
Chen, Yi
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2019/01/08
Cananga odorata essential oil reverses the anxiety induced by 1-(3-chlorophenyl) piperazine through regulating the MAPK pathway and serotonin system in mice
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 219, 页码: 23-30
作者:
Zhang, Nan
;
Zhang, Lei
;
Feng, Linyin
;
Yao, Lei
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
Cananga odorata
1-(3-Chlorophenyl) piperazine
Anxiolytic effect
MAPK
5-HT
Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Xie, Wei
;
Ye, Yangliang
;
Feng, Ying
;
Xu, Tifei
;
Huang, Suling
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
cAMP
gluconeogenesis
linderane
phosphodiesterase
type 2 diabetes
Baicalein and baicalin alleviate acetaminophen-induced liver injury by activating Nrf2 antioxidative pathway: The involvement of ERK1/2 and PKC
期刊论文
Biochemical pharmacology, 2018, 卷号: 150, 页码: 9-23
作者:
Shi, Liang
;
Hao, Zhanxia
;
Zhang, Shaobo
;
Wei, Mengjuan
;
Lu, Bin
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
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