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科研机构
上海药物研究所 [8]
生态环境研究中心 [2]
合肥物质科学研究院 [2]
植物研究所 [1]
内容类型
期刊论文 [13]
发表日期
2020 [13]
学科主题
Plant Scie... [1]
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Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Zheng, Yuan-dong
;
Zhang, Hua
;
Zhan, Yan
;
Bian, Yi-cong
;
Ma, Sheng
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/05/24
vicagrel
[C-14]vicagrel
vicagrel pharmacokinetics
vicagrel metabolism
mass balance
P2Y(12) receptor inhibitor
Direct quantification of anorethidrani disuccinate and determination of sterol metabolites by chemical derivatization combined with LC-MS/MS: Application to a Phase I pharmacokinetic study in humans
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1157, 页码: 9
作者:
Jiang, Jinfang
;
Li, Liang
;
Lu, Youming
;
Chen, Yunhui
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/12/24
Anorethidrani disuccinate
ACP
Sterol metabolite
Glycidyl trimethyl ammonium chloride
LC-MS/MS
Systematic comparison of metabolic differences of Uncaria rhynchophylla in rat, mouse, dog, pig, monkey and human liver microsomes
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 页码: 7
作者:
Li, Hao-Jv
;
Wei, Wen-Long
;
Li, Zhen-Wei
;
Yao, Chang-Liang
;
Wang, Meng-Yuan
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2020/12/24
Uncaria rhynchophylla
Indole alkaloids
Mass defect filter
Time-staggered targeted ion lists
Metabolite identification
Liver microsomes
Combined Metabolomic Analysis of Plasma and Tissue Reveals a Prognostic Risk Score System and Metabolic Dysregulation in Esophageal Squamous Cell Carcinoma
期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:
Chen, Zhongjian
;
Dai, Yalan
;
Huang, Xiancong
;
Chen, Keke
;
Gao, Yun
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/11/30
esophageal squamous cell carcinoma (ESCC)
metabolomics
risk score
prognosis
diagnosis
indoleamine 2
3-dioxygenase 1 (IDO1)
artificial intelligence
Simultaneous determination of sutetinib and its active metabolite sutetinibN-oxide in human plasma by liquid chromatography-tandem mass spectrometry: Evaluation of plasma stability
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 9
作者:
Qiu, Yanan
;
Tang, Chongzhuang
;
Li, Ranran
;
Cao, Sumin
;
Zhang, Yuqiang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/24
LC-MS
MS
N-oxide
stability
sutetinib
Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Tian, Qian-qian
;
Zhu, Yun-ting
;
Diao, Xing-xing
;
Zhang, Xiang-lei
;
Xu, Ye-chun
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2020/12/24
PDE5 inhibitor
TPN729
M3
species difference
pharmacokinetics
metabolite identification
Quantitation of serum pregnanediol-3-glucuronide level in different endocrine statuses by LC-MS/MS
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 184
作者:
Chen, Jian
;
Hou, Hongwei
;
Chen, Huan
;
Luo, Yanbo
;
He, Yunlu
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/11/26
Pregnanediol-3-glucuronide
Serum
LC-MS/MS
Thyroid cancer
Pregnancy
Qualitative and quantitative determination of anaprazole and its major metabolites in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 183, 页码: 10
作者:
Tang, Chongzhuang
;
Li, Liang
;
Ma, Xifeng
;
Wang, Jin
;
Chen, Bo
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/07/01
Metabolite identification
LC-MS/MS
UPLC-UV/Q-TOF
Anaprazole
Deciphering the particle specific effects on metabolism in rat liver and plasma from ZnO nanoparticles versus ionic Zn exposure
期刊论文
ENVIRONMENT INTERNATIONAL, 2020, 卷号: 136, 页码: 1-8
作者:
Guo, Zhiling
;
Luo, Yali
;
Zhang, Peng
;
Chetwynd, Andrew J.
;
Xie, Heidi Qunhui
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/09/14
Zinc oxide nanoparticles
Zinc ions
Metabolite profile
Energy metabolism, oxidative stress
Enrichment of imidacloprid and its metabolites in lizards and its toxic effects on gonads
期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 258, 页码: 1-10
作者:
Yang, Lu
;
Shen, Qiuxuan
;
Zeng, Tao
;
Li, Jianzhong
;
Li, Wei
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/09/15
Lizards
Neonicotinoids
Endocrine disruption
Imidacloprid
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