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上海药物研究所 [39]
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期刊论文 [90]
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Targeted Proteomics Combined with Affinity Mass Spectrometry Analysis Reveals Antagonist E7 Acts As an Intracellular Covalent Ligand of Orphan Receptor GPR52
期刊论文
ACS CHEMICAL BIOLOGY, 2020, 卷号: 15, 期号: 12, 页码: 3275-3284
作者:
Ma, Mengna
;
Guo, Shimeng
;
Lin, Xi
;
Li, Shanshan
;
Wu, Yiran
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/05/24
Computational Insights into the Conformational Accessibility and Binding Strength of SARS-CoV-2 Spike Protein to Human Angiotensin-Converting Enzyme 2
期刊论文
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2020, 卷号: 11, 期号: 24, 页码: 10482-10488
作者:
Peng, Cheng
;
Zhu, Zhengdan
;
Shi, Yulong
;
Wang, Xiaoyu
;
Mu, Kaijie
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/05/24
1-Phenyl-N-(benzothiazol-2-yl)methanimine derivatives as Middle East respiratory syndrome coronavirus inhibitors
期刊论文
RSC ADVANCES, 2020, 卷号: 10, 期号: 71, 页码: 43299-43311
作者:
Hu, Min-Qi
;
Li, Heng
;
Lin, Ying
;
Zhang, Ying
;
Tang, Jie
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/05/24
Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298
作者:
Ding, Chunyong
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Immunotherapy
Anti-tumor
cGAS
STING
TBK1
Small molecule modulators
TWIRLS, a knowledge-mining technology, suggests a possible mechanism for the pathological changes in the human host after coronavirus infection via ACE2
期刊论文
DRUG DEVELOPMENT RESEARCH, 2020, 卷号: 81, 期号: 8, 页码: 1004-1018
作者:
Ji, Xiaoyang
;
Tan, Wenting
;
Zhang, Chunming
;
Zhai, Yubo
;
Hsueh, Yiching
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/12/01
coronavirus
cytokine storm
literature mining
renin‐
angiotensin system
topic inference
A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor
期刊论文
CELL RESEARCH, 2020, 页码: 11
作者:
Sun, Wen
;
Chen, Li-Nan
;
Zhou, Qingtong
;
Zhao, Li-Hua
;
Yang, Dehua
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/12/24
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yu, Ming-cheng
;
Yang, Feng
;
Ding, Xiao-yu
;
Sun, Nan-nan
;
Jiang, Zheng-yuan
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/12/24
RORγ
t
cocrystal structures
MD simulation
“
short”
inverse agonists
agonists
“
long”
inverse agonists
Evaluation of the Estrogenic/Antiestrogenic Activities of Perfluoroalkyl Substances and Their Interactions with the Human Estrogen Receptor by Combining In Vitro Assays and In Silico Modeling
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 22, 页码: 14514-14524
作者:
Li, Juan
;
Cao, Huiming
;
Feng, Hongru
;
Xue, Qiao
;
Zhang, Aiqian
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/09/14
TCDD-induced antagonism of MEHP-mediated migration and invasion partly involves aryl hydrocarbon receptor in MCF7 breast cancer cells
期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2020, 卷号: 398, 页码: 1-10
作者:
Shan, Anqi
;
Leng, Ling
;
Li, Jing
;
Luo, Xiu-mei
;
Fan, Ya-jiao
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/09/14
Coexposure
Antagonism
AhR
Migration
Invasion
Transcriptomic analysis and expression of C-type lectins in response to Vibrio parahaemolyticus challenge in Scapharca subcrenata
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2020, 卷号: 106, 页码: 365-373
作者:
Lin, Jiliang
;
Ning, Junhao
;
Lu, Xia
;
Chen, Min
;
Cao, Weian
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/06/21
Scapharca subcrenata
Transcriptome
Maternal immunity
C-type lectin
Expression analysis
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