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上海药物研究所 [22]
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西北高原生物研究所 [2]
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期刊论文 [30]
发表日期
2020 [30]
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Diphyllin Improves High-Fat Diet-Induced Obesity in Mice Through Brown and Beige Adipocytes
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2020, 卷号: 11, 页码: 13
作者:
Duan, Ya-Nan
;
Ge, Xiang
;
Jiang, Hao-Wen
;
Zhang, Hong-Jie
;
Zhao, Yu
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/05/24
diphyllin
obesity
brown adipocyte
differentiation
thermogenesis
V-ATPase
A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2020, 卷号: 16, 期号: 12, 页码: 20
作者:
Zhang, Haiping
;
Yang, Yang
;
Li, Junxin
;
Wang, Min
;
Saravanan, Konda Mani
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  |  
浏览/下载:42/0
  |  
提交时间:2021/12/01
Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11
作者:
Wang, Yuwei
;
Tang, Shuai
;
Lai, Huanling
;
Jin, Ruyi
;
Long, Xu
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  |  
浏览/下载:50/0
  |  
提交时间:2020/12/24
IDH1
gliomas
molecular docking
virtual screening
docking-based virtual screening
Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 9
作者:
Yang, Longhe
;
Ji, Chunyan
;
Li, Yitian
;
Hu, Fan
;
Zhang, Fang
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  |  
浏览/下载:21/0
  |  
提交时间:2020/12/10
NAAA inhibitor
atractylodin
>
anti-inflammation
microglia
traditional Chinese medicine
A novel thrombin inhibitory peptide discovered from leech using affinity chromatography combined with ultra-high performance liquid chromatography-high resolution mass spectroscopy
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1151, 页码: 8
作者:
Huang, Qiuyang
;
Gao, Qian
;
Chai, Xiaoxin
;
Ren, Wei
;
Zhang, Guifeng
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  |  
浏览/下载:21/0
  |  
提交时间:2020/07/23
Thrombin
Bioactive Compound Screening
Affinity Chromatography
Uplc-hr-ms
Leech
Thrombin Inhibitory Activity
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
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  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9
作者:
Han, Jie
;
Tian, Yucheng
;
Yu, Liang
;
Zhang, Qilin
;
Xu, Xi
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  |  
浏览/下载:64/0
  |  
提交时间:2020/12/24
Ubiquitination
High throughput screening
Drug discovery
USP8
Pharmacologically inhibiting phosphoglycerate kinase 1 for glioma with NG52
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
作者:
Wang, Wen-liang
;
Jiang, Zong-ru
;
Hu, Chen
;
Chen, Cheng
;
Hu, Zhen-quan
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  |  
浏览/下载:27/0
  |  
提交时间:2020/11/26
PGK1
NG52
kinase inhibitor
Warburg effect
glioma
USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines
期刊论文
FEBS JOURNAL, 2020, 页码: 18
作者:
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Xiong, Muya
;
Zhu, Mengying
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2020/12/24
colorectal cancer
HDX-MS
inhibitor
USP25
USP28
Vismodegib
In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2020, 卷号: 60, 期号: 6, 页码: 3265-3276
作者:
Zhao, Wenfeng
;
Xiong, Muya
;
Yuan, Xiaojing
;
Li, Minjun
;
Sun, Hongbin
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/24
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