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科研机构
上海药物研究所 [11]
海洋研究所 [2]
合肥物质科学研究院 [2]
植物研究所 [1]
近代物理研究所 [1]
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期刊论文 [17]
发表日期
2020 [17]
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Plant Scie... [1]
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发表日期:2020
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Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5
作者:
Zhang, Bin
;
Liao, Liping
;
Wu, Fan
;
Zhang, Fengcai
;
Sun, Zhongya
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/05/24
SMYD2 inhibitors
Thermal shift assay
Structure-activity relationships
Heavy ion radiation-induced DNA damage mediates apoptosis via the Rp127a-Rp15-MDM2-p53/E2F1 signaling pathway in mouse spermatogonia
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 201, 页码: 12
作者:
Li, Hongyan
;
Zhang, Hong
;
Huang, Guomin
;
Dou, Zhihui
;
Xie, Yi
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/01/12
Ionizing radiation
Reproductive toxicology
Ribosomal stress
MDM2-p53 loop
Apoptosis
Large-scale lysine crotonylation analysis reveals its potential role in spermiogenesis in the Chinese mitten crab Eriocheir sinensis
期刊论文
JOURNAL OF PROTEOMICS, 2020, 卷号: 226, 页码: 9
作者:
Bao, Chenchang
;
Song, Chengwen
;
Liu, Yuan
;
Yang, Yanan
;
Cui, Zhaoxia
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/04/12
Lysine crotonylation
Proteomics
Spermiogenesis
Eriocheir sinensis
Genotoxicity of microcystin-LR in mammalian cells: Implication from peroxynitrite produced by mitochondria
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 195
作者:
Wang, Xiaofei
;
Li, Yintao
;
Xiao, Hourong
;
Zhang, Min
;
Bao, Teng
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/11/26
Microcystin-LR
DNA damage
Peroxynitrite
Mitochondria
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10
作者:
Hou, Zeng
;
Min, Wenjian
;
Zhang, Rukang
;
Niu, Ao
;
Li, Yuanqing
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  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
Histone methylation
SET7
Small-molecule inhibitor
Virtual screening
Molecular probe
Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 7, 页码: 10
作者:
Min, Wenjian
;
Hou, Zeng
;
Zhang, Fang
;
Xie, Shengnan
;
Yuan, Kai
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/07/01
Histone methylation
Lysine methyltransferase
SET7
Small-molecule inhibitor
Virtual screening
Biological roles of LSD1 beyond its demethylase activity
期刊论文
CELLULAR AND MOLECULAR LIFE SCIENCES, 2020
作者:
Gu, Feiying
;
Lin, Yuxin
;
Wang, Zhun
;
Wu, Xiaoxin
;
Ye, Zhenyue
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  |  
浏览/下载:19/0
  |  
提交时间:2020/11/26
LSD1
Demethylase
Ubiquitylation
FBXW7
Non-catalytic
TAF5L functions as transcriptional coactivator of MITF involved in the immune response of the clam Meretrix petechialis
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2020, 卷号: 98, 页码: 1017-1023
作者:
Wang, Di
;
Zhang, Shujing
;
Liu, Baozhong
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  |  
浏览/下载:32/0
  |  
提交时间:2020/09/23
TAF5L
MITF
Innate immunity
Meretrix petechialis
Global characterization of proteome and lysine methylome features in EZH2 wild-type and mutant lymphoma cell lines
期刊论文
JOURNAL OF PROTEOMICS, 2020, 卷号: 213, 页码: 10
作者:
Hao, Bingbing
;
Sun, Mingwei
;
Zhang, Min
;
Zhao, Xiaoxiao
;
Zhao, Lei
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
Lysine methylome
Quantitative proteomics
EZH2
Diffuse large B cell lymphoma
PTM crosstalk
Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 3, 页码: 1337-1360
作者:
Yang, Yaxi
;
Zhang, Rukang
;
Li, Zhaojun
;
Mei, Lianghe
;
Wan, Shili
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
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