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Broad targeting of triptolide to resistance and sensitization for cancer therapy 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:  Hou, Zhen-yan;  Tong, Xiao-pei;  Peng, Yong-bo;  Zhang, Bi-Kui*;  Yan, Miao*
收藏  |  浏览/下载:50/0  |  提交时间:2019/12/03
ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  
Inhibition of ER stress-related IRE1 alpha/CREB/NLRP1 pathway promotes the apoptosis of human chronic myelogenous leukemia cell 期刊论文
MOLECULAR IMMUNOLOGY, 2018, 卷号: 101, 页码: 377-385
作者:  Xu, Zheng;  Wang, Huirui;  Wei, Suhua;  Wang, Zhencheng;  Ji, Guanghou
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/26
PTEN Is Fundamental for Elimination of Leukemia Stem Cells Mediated by GSK126 Targeting EZH2 in Chronic Myelogenous Leukemia 期刊论文
2018, 卷号: 24, 期号: 1, 页码: 145
作者:  Zhou, Jingfeng[1];  Nie, Danian[2];  Li, Juan[3];  Du, Xin[4];  Lu, Yuhong[5]
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/10
Deciphering Key Pharmacological Pathways of Qingdai Acting on Chronic Myeloid Leukemia Using a Network Pharmacology- Based Strategy 期刊论文
MEDICAL SCIENCE MONITOR, 2018, 卷号: 24, 页码: 5668-5688
作者:  Li, Huayao;  Liu, Lijuan;  Liu, Cun;  Zhuang, Jing;  Zhou, Chao
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/11
A Systems Biology-Based Approach to Uncovering Molecular Mechanisms Underlying Effects of Traditional Chinese Medicine Qingdai in Chronic Myelogenous Leukemia, Involving Integration of Network Pharmacology and Molecular Docking Technology 期刊论文
MEDICAL SCIENCE MONITOR, 2018, 卷号: 24, 页码: 4305-4316
作者:  Zhou, Chao;  Liu, LiJuan;  Zhuang, Ling;  Wei, JunYu;  Zhang, TingTing
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/11
Induction of apoptosis and erythroid differentiation of human chronic myelogenous leukemia K562 cells by low concentrations of lidamycin. 期刊论文
Oncology reports, 2018
作者:  Zhang Chu;  Guo Lu-Ying;  Mu Dan;  Gong Jian-Hua;  Chen Jing
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/26
LncRNA MALAT1 promotes cell proliferation and imatinib resistance by sponging miR-328 in chronic myelogenous leukemia 期刊论文
Biochemical and Biophysical Research Communications, 2018, 卷号: 507, 期号: 1-4, 页码: 1-8
作者:  Wen, Feng*;  Cao, Yi-Xiong;  Luo, Ze-Yu;  Liao, Pei;  Lu, Zhong-Wei
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/27


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