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大连理工大学 [8]
青岛生物能源与过程研... [2]
海洋研究所 [1]
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期刊论文 [11]
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2019 [1]
2016 [4]
2015 [3]
2014 [2]
2013 [1]
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Systems analysis of phosphorylation-regulated Bcl-2 interactions establishes a model to reconcile the controversy over the significance of Bcl-2 phosphorylation
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 页码: 491-504
作者:
Song, Ting
;
Wang, Peiran
;
Yu, Xiaoyan
;
Wang, Anhui
;
Chai, Gaobo
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/02
Deactivation of Mcl-1 by Dual-Function Small-Molecule Inhibitors Targeting the Bcl-2 Homology 3 Domain and Facilitating Mcl-1 Ubiquitination
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 卷号: 55, 期号: 46, 页码: 14248-14254
作者:
Song, Ting
;
Wang, Ziqian
;
Ji, Fangling
;
Feng, Yingang
;
Fan, Yudan
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2017/01/03
apoptosis
conformation analysis
drug design
inhibitors
structure elucidation
Deactivation of Mcl-1 by Dual-Function Small-Molecule Inhibitors Targeting the Bcl-2 Homology 3 Domain and Facilitating Mcl-1 Ubiquitination
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 卷号: 55, 期号: 46, 页码: 14248-14254
作者:
Song, Ting
;
Wang, Ziqian
;
Ji, Fangling
;
Feng, Yingang
;
Fan, Yudan
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2016/12/12
apoptosis
conformation analysis
drug design
inhibitors
structure elucidation
Bcl-2 phosphorylation confers resistance on chronic lymphocytic leukaemia cells to the BH3 mimetics ABT-737, ABT-263 and ABT-199 by impeding direct binding
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2016, 卷号: 173, 页码: 471-483
作者:
Song, Ting
;
Chai, Gaobo
;
Liu, Yubo
;
Yu, Xiaoyan
;
Wang, Ziqian
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/09
Deactivation of Mcl-1 by Dual-Function Small-Molecule Inhibitors Targeting the Bcl-2 Homology 3 Domain and Facilitating Mcl-1 Ubiquitination
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 卷号: 55, 页码: 14248-14254
作者:
Song, Ting
;
Wang, Ziqian
;
Ji, Fangling
;
Feng, Yingang
;
Fan, Yudan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/09
apoptosis
conformation analysis
drug design
inhibitors
structure elucidation
Novel Mcl-1/Bcl-2 Dual Inhibitors Created by the Structure-Based Hybridization of Drug-Divided Building Blocks and a Fragment Deconstructed from a Known Two-Face BH3 Mimetic
期刊论文
ARCHIV DER PHARMAZIE, 2015, 卷号: 348, 页码: 89-99
作者:
Zhang, Zhichao
;
Su, Pengchen
;
Li, Xiangqian
;
Song, Ting
;
Chai, Gaobo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/09
alpha-Helix
Drug-divided building blocks
Fragment-based
Mcl-1
Bcl-2
Discovery of a Small-Molecule pBcl-2 Inhibitor that Overcomes pBcl-2-Mediated Resistance to Apoptosis
期刊论文
CHEMBIOCHEM, 2015, 卷号: 16, 页码: 757-765
作者:
Song, Ting
;
Yu, Xiaoyan
;
Liu, Yubo
;
Li, Xiangqian
;
Chai, Gaobo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/09
apoptosis
Bcl-2
BH3 mimetics
cancer
immunoassays
inhibitors
Mechanism of synergy of BH3 mimetics and paclitaxel in chronic myeloid leukemia cells: Mcl-1 inhibition
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, 卷号: 70, 页码: 64-71
作者:
Song, Ting
;
Chai, Gaobo
;
Liu, Yubo
;
Xie, Mingzhou
;
Chen, Qingbin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/09
CML
Paclitaxel
BH3 mimetics
Synergism
Two-Face, Two-Turn alpha-Helix Mimetics Based on a Cross-Acridine Scaffold: Analogues of the Bim BH3 Domain
期刊论文
CHEMBIOCHEM, 2014, 卷号: 15, 期号: 9, 页码: 1280-1285
作者:
Li, Xiangqian
;
Wang, Ziqian
;
Feng, Yingang
;
Song, Ting
;
Su, Pengchen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2015/11/02
acridines
helical structures
Mcl-1
peptidomimetics
two-face
Two-Face, Two-Turn alpha-Helix Mimetics Based on a Cross-Acridine Scaffold: Analogues of the Bim BH3 Domain
期刊论文
CHEMBIOCHEM, 2014, 卷号: 15, 页码: 1280-1285
作者:
Li, Xiangqian
;
Wang, Ziqian
;
Feng, Yingang
;
Song, Ting
;
Su, Pengchen
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/09
acridines
helical structures
Mcl-1
peptidomimetics
two-face
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