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科研机构
山东大学 [8]
内容类型
期刊论文 [8]
发表日期
2019 [2]
2018 [3]
2017 [3]
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Design, synthesis and antibacterial evaluation of novel 15-membered 11a-azahomoclarithromycin derivatives with the 1, 2, 3-triazole side chain
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 321-339
作者:
Qin, Yinhui
;
Teng, Yuetai
;
Ma, Ruixin
;
Bi, Fangchao
;
Liu, Zhiyang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/11
Macrolide antibiotics
Antibacterial activity
Resistant bacterial
strains
Structure-activity relationships
Discovery of 1,3,4-oxadiazol-2-one-containing benzamide derivatives targeting FtsZ as highly potent agents of killing a variety of MDR bacteria strains
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 14, 页码: 3179-3193
作者:
Bi, Fangchao
;
Song, Di
;
Qin, Yinhui
;
Liu, Xingbang
;
Teng, Yuetai
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/11
1,3,4-Oxadiazol-2-one-containing benzamides
FtsZ-targeting
Multidrug-resistant bacteria
Antibacterial activity
Novel 5-methyl-2-phenylphenanthridium derivatives as FtsZ-targeting antibacterial agents from structural simplification of natural product sanguinarine
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 10, 页码: 1825-1831
作者:
Liu, Jingru
;
Ma, Ruxin
;
Bi, Fangchao
;
Zhang, Fa
;
Hu, Chaoyu
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/16
Antibacterial activity
FtsZ-targetingantibacterial agents
5-Methyl-2-phenylphenanthridium derivatives
Structural simplification
Substitution of terminal amide with 1H-1,2,3-triazole: Identification of unexpected class of potent antibacterial agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 5, 页码: 884-891
作者:
Bi, Fangchao
;
Ji, Shengli
;
Venter, Henrietta
;
Liu, Jingru
;
Semple, Susan J.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
1H-1,2,3-Triazole
Terminal amide
Mimic
Antibacterial agents
In
silico prediction
Design, synthesis and structure-based optimization of novel isoxazole-containing benzamide derivatives as FtsZ modulators
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 159, 页码: 90-103
作者:
Bi, Fangchao
;
Song, Di
;
Zhang, Nan
;
Liu, Zhiyang
;
Gu, Xinjie
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
Isoxazole-containing benzamide
Antibacterial activity
FtsZ inhibitor
Molecular docking analysis
Structure-based optimization
Discovery and Optimization of NAD(+)-Dependent DNA Ligase Inhibitors as Novel Antibacterial Compounds
期刊论文
CURRENT PHARMACEUTICAL DESIGN, 2017, 卷号: 23, 期号: 14, 页码: 2117-2130
作者:
Bi, Fangchao
;
Ma, Ruixin
;
Ma, Shutao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
DNA ligases
LigAs
inhibitors
antibacterial
HTS
VS
Design, synthesis and biological activity evaluation of novel 2,6-difluorobenzamide derivatives through FtsZ inhibition
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 4, 页码: 958-962
作者:
Bi, Fangchao
;
Guo, Liwei
;
Wang, Yinhu
;
Venter, Henrietta
;
Semple, Susan J.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/12
Benzamide derivatives
Design and synthesis
FtsZ inhibition
Biological
activity
Synthesis and antibacterial activity of 5-methylphenanthridium derivatives as FtsZ inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 15, 页码: 3399-3402
作者:
Liu, Fang
;
Venter, Henrietta
;
Bi, Fangchao
;
Semple, Susan J.
;
Liu, Jingru
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/12
Antimicrobials
Biological evaluation
FtsZ
Structure-activity
relationships
5-Methylphenanthridium derivatives
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