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浏览/检索结果: 共6条，第1-6条 帮助 限定条件 发表日期：2021     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64 作者:  Fu, Weitao;  Zhang, Minkui;  Liao, Jianing;  Tang, Qing;  Lei, Yixuan 收藏  |  浏览/下载：49/0  |  提交时间：2022/03/21 Protein degradation technology: a strategic paradigm shift in drug discovery 期刊论文 JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021, 卷号: 14 作者:  Li, Haobin;  Dong, Jinyun;  Cai, Maohua;  Xu, Zhiyuan;  Cheng, Xiang-Dong 收藏  |  浏览/下载：30/0  |  提交时间：2021/11/01 Protein degradation  Degradation pathway  Degradation technology  PROTAC  Monomeric degraders   PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy 期刊论文 FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12 作者:  Qi, Si-Min;  Dong, Jinyun;  Xu, Zhi-Yuan;  Cheng, Xiang-Dong;  Zhang, Wei-Dong 收藏  |  浏览/下载：47/0  |  提交时间：2021/06/15 PROTAC  E3 ubiquitin ligase  protein degradation  ubiquitin-proteasome system  cancer therapy   Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 18 作者:  Bernasocchi, Tiziano;  El Tekle, Geniver;  Bolis, Marco;  Mutti, Azzurra;  Vallerga, Arianna 收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24 Design, synthesis and biological evaluation of novel thiohydantoin derivatives as potent androgen receptor antagonists for the treatment of prostate cancer 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 31, 页码: 13 作者:  Wang, Ao;  Wang, Yawan;  Meng, Xin;  Yang, Yushe 收藏  |  浏览/下载：14/0  |  提交时间：2021/05/24 Androgen receptor  Novel thiohydantoin derivatives  Androgen receptor antagonists  Prostate cancer   A Deep Insight of Spermatogenesis and Hormone Levels of Aqua-Cultured Turbot (Scophthalmus maximus) 期刊论文 FRONTIERS IN MARINE SCIENCE, 2021, 卷号: 7, 页码: 17 作者:  Liu, Yifan;  Liu, Qinghua;  Xu, Shihong;  Wang, Yanfeng;  Feng, Chengcheng 收藏  |  浏览/下载：42/0  |  提交时间：2021/04/21 fish reproduction  spermatogenesis  factory farmed fish  steroids  Scophthalmus maximus