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Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway
期刊论文
PHYTOMEDICINE, 2023, 卷号: 108
作者:
Hu, Yiqun
;
Wen, Qingliang
;
Cai, Yefeng
;
Liu, Yunye
;
Ma, Wenli
收藏
  |  
浏览/下载:173/0
  |  
提交时间:2022/12/23
Alantolactone
Anaplastic thyroid cancer
ROS
Pyroptosis
Apoptosis
Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors (vol 0, pg 1, 2022)
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Guo-zhen
;
Ma, Li-ying
;
Zhang, Zong-hui
;
Wang, Xiao-lin
;
Hua, Jing-han
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/23
Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Guo-Zhen
;
Ma, Li-Ying
;
Zhang, Zong-Hui
;
Wang, Xiao-Lin
;
Hua, Jing-Han
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/12/22
small-cell lung cancer
H3
3
PARP1
PARP inhibitor
darinaparsin
combination treatment
Vanguard is a Glucose Deprivation-Responsive Long Non-Coding RNA Essential for Chromatin Remodeling-Reliant DNA Repair
期刊论文
ADVANCED SCIENCE, 2022
作者:
Zhang, Ben
;
Thorne, Rick Francis
;
Zhang, Pengfei
;
Wu, Mian
;
Liu, Lianxin
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/12/23
genomic stability
HMGB1
long non-coding RNAs
PARP inhibitors
Vanguard
Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib
期刊论文
BMC CANCER, 2022, 卷号: 22
作者:
Jin, Ying
;
Lin, Chen
;
Shi, Xun
;
He, Qiong
;
Yan, Junrong
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/12/23
Clinical and molecular features
Efficacy and outcome
EGFR T790M mutation
Non-small-cell lung cancer
Osimertinib
Olaparib maintenance monotherapy in Chinese patients with platinum-sensitive relapsed ovarian cancer: China cohort from the phase III SOLO2 trial
期刊论文
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2022
作者:
Liu, Jihong
;
Yin, Rutie
;
Wu, Lingying
;
Zhu, Jianqing
;
Lou, Ge
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/05/05
BRCA mutation
China
olaparib
ovarian cancer
PARP inhibitor
Pamiparib Monotherapy for Patients with Germline BRCA1/2-Mutated Ovarian Cancer Previously Treated with at Least Two Lines of Chemotherapy: A Multicenter, Open-Label, Phase II Study
期刊论文
CLINICAL CANCER RESEARCH, 2022, 卷号: 28
作者:
Wu, Xiaohua
;
Zhu, Jianqing
;
Wang, Jing
;
Lin, Zhongqiu
;
Yin, Rutie
收藏
  |  
浏览/下载:102/0
  |  
提交时间:2022/03/28
PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery
期刊论文
AUTOPHAGY, 2021, 卷号: 17, 期号: 10, 页码: 2905-2922
作者:
Tang, Ying
;
Liu, Jinchang
;
Wang, Yu
;
Yang, Li
;
Han, Bing
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/01/04
Autophagy
functional recovery
ischemic stroke
lysophosphatidic acid receptor 5
microglial activation
poly (ADP-ribose) polymerase 14
Constitutive BAK/MCL1 complexes predict paclitaxel and S63845 sensitivity of ovarian cancer
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12
作者:
Liu, Dongyan
;
Hou, Xiaonan
;
Wu, Wangyu
;
Zafagnin, Valentina
;
Li, Yunjian
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/09/06
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:91/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
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