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科研机构
上海药物研究所 [103]
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期刊论文 [101]
会议论文 [2]
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2021 [1]
2020 [2]
2019 [6]
2018 [4]
2017 [1]
2016 [3]
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Challenges and stepwise fit-for-purpose optimization for bioanalyses of remdesivir metabolites nucleotide monophosphate and triphosphate in mouse tissues using LC-MS/MS
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 194, 页码: 10
作者:
Hu, Wenjuan
;
Chang, Lu
;
Ke, Changqiang
;
Xie, Yuanchao
;
Shen, Jingshan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
Remdesivir
Nucleotide monophosphate
Nucleotide triphosphate
Stability
Recovery
LC-MS/MS
Qualitative and quantitative determination of anaprazole and its major metabolites in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 183, 页码: 10
作者:
Tang, Chongzhuang
;
Li, Liang
;
Ma, Xifeng
;
Wang, Jin
;
Chen, Bo
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2020/07/01
Metabolite identification
LC-MS/MS
UPLC-UV/Q-TOF
Anaprazole
Quantification of microbiota-related phenols and aromatic acids in mouse feces of a diabetic nephropathy model by simultaneous BDAPE derivatization using ultra-performance liquid chromatography-tandem mass spectrometry
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 卷号: 412, 期号: 13, 页码: 3241-3252
作者:
Zheng, Xiaoli
;
Duan, Haonan
;
Lin, Feifei
;
Li, Xiaomei
;
Shen, Jianhua
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Phenols
Aromatic acid
Microbiota
Uremic toxin
Simultaneous derivatization
2-Bromo-1-[4-(dimethylamino)phenyl] ethyl ketone
Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 176, 页码: 6
作者:
Liu, Xiaoyun
;
Li, Wei
;
Zhang, Yifan
;
Jian, Yong
;
Zhao, Qianyu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
LC-MS/MS
Alflutinib
AST2818
Pharmacokinetics
Human plasma
Enantioselective determination of ketamine in dog plasma by chiral liquid chromatography-tandem mass spectrometry
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2019, 卷号: 33, 期号: 9, 页码: 8
作者:
Li, Ranran
;
Zhong, Kan
;
Jiang, Jinfang
;
Zhan, Yuan
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
chiral stationary phases
enantioselective LC-MS
MS
ketamine
stereoselective pharmacokinetics
Simultaneous determination of resibufogenin and its eight metabolites in rat plasma by LC-MS/MS for metabolic profiles and pharmacokinetic study
期刊论文
PHYTOMEDICINE, 2019, 卷号: 60, 页码: 7
作者:
Wei, Wen-long
;
An, Ya-ling
;
Li, Zhen-wei
;
Wang, Ying-ying
;
Ji, Hong-jian
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
Resibufogenin
Metabolites
Quantitation
Pharmacokinetics
Metabolic profiles
Sensitive Water-Soluble Fluorescent Probe Based on Umpolung and Aggregation-Induced Emission Strategies for Selective Detection of Hg2+ in Living Cells and Zebrafish
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 8, 页码: 2377-2383
作者:
Gao, Tang
;
Huang, Xueyan
;
Huang, Shuai
;
Dong, Jie
;
Yuan, Kai
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
umpolung
aggregation-induced emission
fluorescent probe
detection of Hg2+
cell imaging
zebrafish imaging
Assay development for determination of DZ2002, a new reversible SAHH inhibitor, and its acid metabolite DZA in blood and application to rat pharmacokinetic study
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2019, 卷号: 9, 期号: 1, 页码: 25-33
作者:
Jia, Weiwei
;
Li, Jing
;
Du, Feifei
;
Sun, Yan
;
Xu, Fang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
S-adenosyl-L-homocysteine hydrolase
DZ2002
Carboxylesterases
Pharmacokinetics
assaydevelopmentfordeterminationofdz2002anewreversiblesahhinhibitoranditsacidmetabolitedzainbloodandapplicationtoratpharmacokineticstudy
期刊论文
药物分析学报英文版, 2019, 卷号: 009, 期号: 001, 页码: 25
作者:
Weiwei Jia
;
Jing Li
;
Feifei Du
;
Yan Sun
;
Fang Xu
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
S-adenosyl-L-homocysteine
hydrolase
DZ2002
Carboxylesterases
Pharmacokinetics
Development of an LC-MS/MS-based assay to determine artemitin in rat plasma and its application in a pharmacokinetic study
期刊论文
Biomedical chromatography : BMC, 2018, 卷号: 32, 期号: 12, 页码: e4356
作者:
Han, Xiaoli
;
He, Jinhua
;
Chen, Qinyue
;
Sun, Yali
;
Zhang, Xiulei
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
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