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科研机构
上海药物研究所 [5380]
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期刊论文 [3965]
项目 [1282]
会议论文 [123]
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Novel pectin-like polysaccharide from Panax notoginseng attenuates renal tubular cells fibrogenesis induced by TGF-beta
期刊论文
CARBOHYDRATE POLYMERS, 2022, 卷号: 276, 页码: 12
作者:
Huang, Chunfan
;
Jing, Xiaoqi
;
Wu, Qianhu
;
Ding, Kan
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/12/16
Panax notoginseng
Polysaccharide
Renal fibrosis
Epithelial-mesenchymal transition
Pectin
Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy of orthotopic osteosarcoma (vol 417, 128103, 2021)
期刊论文
CHEMICAL ENGINEERING JOURNAL, 2022, 卷号: 428, 页码: 2
作者:
Geng, Huan
;
Zhou, Mengxue
;
Li, Bin
;
Liu, Liang
;
Yang, Xu
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  |  
浏览/下载:33/0
  |  
提交时间:2022/01/18
Cocktail polysaccharides isolated from Ecklonia kurome against the SARS-CoV-2 infection
期刊论文
CARBOHYDRATE POLYMERS, 2022, 卷号: 275, 页码: 8
作者:
Zhang, Shihai
;
Pei, Rongjuan
;
Li, Meixia
;
Su, Haixia
;
Sun, Hao
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  |  
浏览/下载:69/0
  |  
提交时间:2021/12/16
COVID-19
SARS-CoV-2
Angiotensin converting enzyme 2 (ACE2)
3CL protease
Ecklonia kurome Okam
Polysaccharide
Synthesis and antiviral activity of 2 '-deoxy-6 '-substituted carbocyclic nucleosides
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 12
作者:
Xue, Haitao
;
Guo, Shuang
;
Hu, Tianwen
;
Wei, Daibao
;
Xie, Yuanchao
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  |  
浏览/下载:37/0
  |  
提交时间:2022/01/18
2 '-deoxy carbocyclic nucleoside
antiviral activity
hepatitis B virus
Mitsunobu reaction
National Science & Technology Major Project Key New Drug Creation and Manufacturing Program, China[2019ZX09301157-003]
项目
项目编号: 2019ZX09301157-003, 资助机构: National Science & Technology Major Project Key New Drug Creation and Manufacturing Program, China, 2021-
-
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  |  
浏览/下载:2/0
  |  
提交时间:2022/01/18
Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:
Yang, Xiangbo
;
Lu, Huimin
;
Xie, Hang
;
Zhang, Binbin
;
Nie, Tianqing
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  |  
浏览/下载:24/0
  |  
提交时间:2022/01/18
Binding studies
Drug discovery
Necroptosis
RIPK1 inhibitors
Sepsis
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
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  |  
浏览/下载:61/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12050202]
项目
项目编号: XDA12050202, 资助机构: Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences, 2021-
-
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  |  
浏览/下载:164/0
  |  
提交时间:2021/05/24
State Key Laboratory of Drug Research of Shanghai Institute of Materia Medica[Y5G203F018]
项目
项目编号: Y5G203F018, 资助机构: State Key Laboratory of Drug Research of Shanghai Institute of Materia Medica, 2021-
-
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  |  
浏览/下载:167/0
  |  
提交时间:2021/05/24
Accucopy: accurate and fast inference of allele-specific copy number alterations from low-coverage low-purity tumor sequencing data
期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22, 期号: 1, 页码: 18
作者:
Fan, Xinping
;
Luo, Guanghao
;
Huang, Yu S.
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  |  
浏览/下载:214/0
  |  
提交时间:2021/05/24
Cancer genomics
Copy number alterations
Next-generation sequencing
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