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Mutation L1196M-induced conformational changes and the drug resistant mechanism of anaplastic lymphoma kinase studied by free energy perturbation and umbrella sampling 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 44, 页码: 30239-30248
作者:  Chen, Jianzhong;  Wang, Jinan;  Zhu, Weiliang
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Biomimetic Magnetosomes as Versatile Artificial Antigen-Presenting Cells to Potentiate T-Cell-Based Anticancer Therapy 期刊论文
ACS NANO, 2017, 卷号: 11, 期号: 11, 页码: 10724-10732
作者:  Zhang, Qanmei;  Wei, Wei;  Wang, Peilin;  Zuo, Liping;  Li, Feng
收藏  |  浏览/下载:36/0  |  提交时间:2018/01/19
DCZ3301, a novel cytotoxic agent, inhibits proliferation in diffuse large B-cell lymphoma via the STAT3 pathway 期刊论文
CELL DEATH & DISEASE, 2017, 卷号: 8
作者:  Sun, Xi;  Li, Bo;  Xie, Bingqian;  Xu, Zhijian;  Chang, Gaomei
收藏  |  浏览/下载:61/0  |  提交时间:2019/01/08
Structure-activity relationship investigation for benzonaphthyridinone derivatives as novel potent Bruton's tyrosine kinase (BTK) irreversible inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 545-557
作者:  Wang, Beilei;  Deng, Yuanxin;  Chen, Yongfei;  Yu, Kailin;  Wang, Aoli
收藏  |  浏览/下载:39/0  |  提交时间:2018/08/16
Dietary protein levels regulated antibacterial activity, inflammatory response and structural integrity in the head kidney, spleen and skin of grass carp (Ctenopharyngodon idella) after challenged with Aeromonas hydrophila 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 68, 期号: 1, 页码: 154-172
作者:  Jiang, Wei-Dan;  Xu, Jing;  Zhou, Xiao-Qiu;  Wu, Pei;  Liu, Yang
收藏  |  浏览/下载:21/0  |  提交时间:2019/09/26
Dietary myo-inositol deficiency decreased the growth performances and impaired intestinal physical barrier function partly relating to nrf2, jnk, e2f4 and mlck signaling in young grass carp (Ctenopharyngodon idella) 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 67, 期号: 1, 页码: 475-492
作者:  Li, Shuang-An;  Jiang, Wei-Dan;  Feng, Lin;  Liu, Yang;  Wu, Pei
收藏  |  浏览/下载:21/0  |  提交时间:2019/08/01
Decreased enteritis resistance ability by dietary low or excess levels of lipids through impairing the intestinal physical and immune barriers function of young grass carp (Ctenopharyngodon idella) 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 67, 期号: 1, 页码: 493-512
作者:  Feng, Lin;  Ni, Pei-Jun;  Jiang, Wei-Dan;  Wu, Pei;  Liu, Yang
收藏  |  浏览/下载:17/0  |  提交时间:2019/08/01
Potent, Selective, and Cell Active Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor Developed by Structure-Based Virtual Screening and Hit Optimization 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 14, 页码: 6289-6304
作者:  Mao, Ruifeng;  Shao, Jingwei;  Zhu, Kongkai;  Zhang, Yuanyuan;  Ding, Hong
收藏  |  浏览/下载:91/0  |  提交时间:2019/01/08
Model-free feature screening for ultrahigh dimensional censored regression 期刊论文
STATISTICS AND COMPUTING, 2017, 卷号: 27, 期号: 4, 页码: 947-961
作者:  Zhou, Tingyou;  Zhu, Liping
收藏  |  浏览/下载:5/0  |  提交时间:2019/08/22
The decreased growth performance and impaired immune function and structural integrity by dietary iron deficiency or excess are associated with TOR, NF-kappa B, p38MAPK, Nrf2 and MLCI(signaling in head kidney, spleen and skin of grass carp (Ctenopharyngodon idella) 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 65, 期号: 1, 页码: 145-168
作者:  Guo, Yan-Lin;  Jiang, Wei-Dan;  Wu, Pei;  Liu, Yang;  Zhou, Xiao-Qiu
收藏  |  浏览/下载:18/0  |  提交时间:2019/09/02


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