QQ客服 官方微博 反馈留言

浏览/检索结果: 共6条，第1-6条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer 期刊论文 ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 67071-67086 作者:  Qian, Jianchang;  Chen, Yaqing;  Meng, Tao;  Ma, Lanping;  Meng, Lanfang 收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 mTOR kinase inhibitor  mTORC2  apoptosis  lipid metabolism   HSP90 inhibitor AUY922 abrogates up-regulation of RTKs by mTOR inhibitor AZD8055 and potentiates its antiproliferative activity in human breast cancer 期刊论文 INTERNATIONAL JOURNAL OF CANCER, 2014, 卷号: 135, 期号: 10, 页码: 2462-2474 作者:  Chen, Si-Meng;  Guo, Chen-Liang;  Shi, Jia-Jie;  Xu, Yi-Chao;  Chen, Yi 收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 mTOR kinase inhibitor  HSP90 inhibitor  breast cancer  receptor tyrosine kinases  drug combination   SIRT1 in cardiovascular aging 期刊论文 Clinica Chimica Acta, 2014, 卷号: 437, 页码: 106-114 作者:  Luo, Xin-Yuan;  Qu, Shun-Lin;  Tang, Zhi-Han;  Zhang, Yuan;  Liu, Mi-Hua 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/27 CVD  cardiovascular disease  SIRT1  sirtuin1  LV  left ventricular  Sir2  silent information regulator 2  rDNA  recombinant DNA  PI3K  phosphoinositide 3-hydroxykinase  NF-κB  nuclear factor kappa B  FOXOs  forkhead box O transcription factors  ROS  reactive oxygen species  mTOR  mammalian (or mechanistic) target of rapamycin  H2O2  hydrogen peroxide  NO  nitric oxide  GADD45  DNA damage-inducible protein 45  MnSOD  manganese superoxide dismutase  H2S  hydrogen sulfide  HUVECs  human umbilical vein endothelial cells  eNOS  endothelial nitric oxide synthase  miR  microRNA  CR  caloric restriction  AP-1  activator protein 1  STACs  small molecule activators of SIRT1  mTORC1  mTOR complex 1  mTORC2  mTOR complex 2  LC  light chain  IGF  insulin-like growth factor  Atgs  autophagy-related genes  SIRT1  Cardiovascular aging  Oxidative stress  Inflammation  Autophagy  Anti-aging strategies   The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling 期刊论文 http://dx.doi.org/10.1002/emmm.201201369, 2013 Wang, Rong-Hao; He, Jian-Ping; Su, Mao-Long; Luo, Jie; Xu, Ming; Du, Xiao-Dan; Chen, Hang-Zi; Wang, Wei-Jia; Wang, Yuan; Zhang, Nan; Zhao, Bi-Xing; Zhao, Wen-Xiu; Shan, Zhong-Gui; Han, Jiahuai; Chang, 收藏  |  浏览/下载：3/0  |  提交时间：2013/12/12 angiotensin II  cardiac hypertrophy  mammalian target of rapamycin  orphan receptor TR3  tuberous sclerosis complex   The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling 期刊论文 http://dx.doi.org/10.1002/emmm.201201369, 2013 Wang, Rong-Hao; He, Jian-Ping; Su, Mao-Long; Luo, Jie; Xu, Ming; Du, Xiao-Dan; Chen, Hang-Zi; Wang, Wei-Jia; Wang, Yuan; Zhang, Nan; Zhao, Bi-Xing; Zhao, Wen-Xiu; Shan, Zhong-Gui; Han, Jiahuai; Chang,Chawnshang; Wu,Qiao 收藏  |  浏览/下载：3/0  |  提交时间：2013/12/12 angiotensin II  cardiac hypertrophy  mammalian target of rapamycin  orphan receptor TR3  tuberous sclerosis complex   Identification of p27/KIP1 expression level as a candidate biomarker of response to rapalogs therapy in human cancer 期刊论文 JOURNAL OF MOLECULAR MEDICINE-JMM, 2010, 卷号: 88, 期号: 9, 页码: 941-952 作者:  Chen, Guang;  Yang, Na;  Wang, Xiang;  Zheng, Si-Yuan;  Chen, Yi 收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 mTOR  Biomarker  p27  Rapamycin  Rapalogs  Cancer